Seven-Year Analysis of Microbial Keratitis Tendency at an Ophthalmology Department in Poland: A Single-Center Study
المؤلفون المشاركون
Wylęgała, Edward
Ulfik, Klaudia
Teper, Sławomir
Dembski, Michał
Nowińska, Anna
Wróblewska-Czajka, Ewa
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-28
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This study aimed to analyze the frequency, drug susceptibility, and drug resistance of pathogens causing microbial keratitis (a corneal inflammation) in the Clinical Department of Ophthalmology, Medical University of Silesia, Katowice.
Despite intensive treatment, severe inflammation causes irreversible blindness in ∼7% of cases and eye loss (evisceration or enucleation of the eyeball) in ∼1% of cases at our hospital.
The choice of a targeted drug depends on the culture result and drug resistance of the microorganism.
This was a retrospective observation study.
Conjunctival swabs and corneal scrapes were collected between January 1, 2013, and December 31, 2019, in the tertiary reference center for keratitis.
The collected data included the type of material received, culture result, and antimicrobial susceptibilities.
Of the 2482 samples analyzed, 679 were positive and 1803 were negative.
Of the total pathogens isolated, 69.9% were Gram-positive bacteria, 20.8% were Gram-negative bacteria, and 7.1% were fungi.
A significant increase in the number of Gram-positive methicillin-resistant Staphylococcus aureus and a partial increase in the number of Gram-negative beta-lactams-resistant bacteria were observed.
All fungal species were sensitive to amphotericin B, 82.81% were sensitive to voriconazole, and 56.25% were sensitive to fluconazole.
Dual drug therapy (levofloxacin and tobramycin) was the first-line treatment.
Drug susceptibility testing of the cultured microorganisms is necessary to initiate targeted treatment.
Increased drug resistance was observed in this study.
In the present study, most bacteria were sensitive to fluoroquinolones.
Ciprofloxacin therapy remains the recommended empirical treatment in microbial keratitis.
According to our study, voriconazole remains a first-line antifungal drug, when a fungal infection is suspected.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ulfik, Klaudia& Teper, Sławomir& Dembski, Michał& Nowińska, Anna& Wróblewska-Czajka, Ewa& Wylęgała, Edward. 2020. Seven-Year Analysis of Microbial Keratitis Tendency at an Ophthalmology Department in Poland: A Single-Center Study. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1189808
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ulfik, Klaudia…[et al.]. Seven-Year Analysis of Microbial Keratitis Tendency at an Ophthalmology Department in Poland: A Single-Center Study. Journal of Ophthalmology No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1189808
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ulfik, Klaudia& Teper, Sławomir& Dembski, Michał& Nowińska, Anna& Wróblewska-Czajka, Ewa& Wylęgała, Edward. Seven-Year Analysis of Microbial Keratitis Tendency at an Ophthalmology Department in Poland: A Single-Center Study. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1189808
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1189808
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر