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Effects of Oral Vitamin B1 and Mecobalamin on Dry Eye Disease
المؤلفون المشاركون
Wang, Yuexin
Chen, Yanyan
Jiang, Xiaodan
Ren, Xiaotong
Chou, Yilin
Li, Xuemin
Hao, Ran
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
To assess the effects of oral vitamin B1 and mecobalamin on dry eye disease (DED) and patient satisfaction with treatment.
Methods.
In this randomized controlled study, DED patients were divided into 4 groups based on treatment: group 1, only artificial tears; group 2, corticosteroid eye drops and artificial tears; group 3, oral vitamin B1, mecobalamin, and artificial tears; and group 4, oral vitamin B1, mecobalamin, corticosteroid eye drops, and artificial tears.
DED symptoms, signs, and patient satisfaction with treatment were assessed at baseline and at 1 and 2 months after treatment.
Results.
In total, 152 eyes from 76 patients (age, 55.25 ± 18.16 years) were included.
In group 3, there were significant differences in dryness, foreign body sensation, burning, and tear film breakup time first (TBUTF) between 1 and 2 months after treatment and in satisfaction scores before and after treatment (P<0.05).
In group 3, there were also significant differences in dryness, foreign body sensation, photophobia, and TBUTA and between baseline and 2 months after treatment (P<0.05).
There was a significant difference in foreign body sensation between 1 and 2 months after treatment in groups 3 and 4 (P<0.05).
Furthermore, we also find obvious improvement in corneal nerve fiber density (CNFD) between baseline and 1 and 2 months after treatment in groups 3 and 4 (P<0.05).
Conclusions.
Oral vitamin B1 and mecobalamin can relieve some dry eye symptoms such as dryness, pain, and photophobia and improve DED signs and patient satisfaction.
Thus, vitamin B1 and mecobalamin are potential treatment options for patients with DED.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ren, Xiaotong& Chou, Yilin& Jiang, Xiaodan& Hao, Ran& Wang, Yuexin& Chen, Yanyan…[et al.]. 2020. Effects of Oral Vitamin B1 and Mecobalamin on Dry Eye Disease. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1189903
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ren, Xiaotong…[et al.]. Effects of Oral Vitamin B1 and Mecobalamin on Dry Eye Disease. Journal of Ophthalmology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1189903
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ren, Xiaotong& Chou, Yilin& Jiang, Xiaodan& Hao, Ran& Wang, Yuexin& Chen, Yanyan…[et al.]. Effects of Oral Vitamin B1 and Mecobalamin on Dry Eye Disease. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1189903
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1189903
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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