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Invasion of Epithelial Cells Is Correlated with Secretion of Biosurfactant via the Type 3 Secretion System (T3SS) of Shigella flexneri
المؤلفون المشاركون
Kayath, Christian Aimé
Nguimbi, Etienne
Kinouani Kinavouidi, Duchel Jeanedvi
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-29
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Biosurfactants are amphipathic molecules produced by many microorganisms, usually bacteria, fungi, and yeasts.
They possess the property of reducing the tension of the membrane interfaces.
No studies have been conducted on Shigella species showing the role of biosurfactant-like molecules (BLM) in pathogenicity.
The aim of this study is to assess the ability of Shigella environmental and clinical strains to produce BLM and investigate the involvement of biosurfactants in pathogenicity.
Our study has shown that BLM are secreted in the extracellular medium with EI24 ranging from 80% to 100%.
The secretion is depending on the type III secretion system (T3SS).
Moreover, our results have shown that S.
flexneri, S.
boydii, and S.
sonnei are able to interact with hydrophobic areas with 17.64%, 21.42%, and 22.22% hydrophobicity, respectively.
BLM secretion is totally prevented due to inhibition of T3SS by 100 mM benzoic and 1.5 mg/ml salicylic acids.
P.
aeruginosa harboring T3SS is able to produce 100% of BLM in the presence or in the absence of both T3SS inhibitors.
The secreted BLM are extractable with an organic solvent such as chloroform, and this could entirely be considered a lipopeptide or polypeptide compound.
Secretion of BLM allows some Shigella strains to induce multicellular phenomena like “swarming.”
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kinouani Kinavouidi, Duchel Jeanedvi& Kayath, Christian Aimé& Nguimbi, Etienne. 2020. Invasion of Epithelial Cells Is Correlated with Secretion of Biosurfactant via the Type 3 Secretion System (T3SS) of Shigella flexneri. Journal of Pathogens،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1190031
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kinouani Kinavouidi, Duchel Jeanedvi…[et al.]. Invasion of Epithelial Cells Is Correlated with Secretion of Biosurfactant via the Type 3 Secretion System (T3SS) of Shigella flexneri. Journal of Pathogens No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1190031
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kinouani Kinavouidi, Duchel Jeanedvi& Kayath, Christian Aimé& Nguimbi, Etienne. Invasion of Epithelial Cells Is Correlated with Secretion of Biosurfactant via the Type 3 Secretion System (T3SS) of Shigella flexneri. Journal of Pathogens. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1190031
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1190031
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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