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In Vitro Anthelmintic Activity of Crude Extracts of Artemisia herba-alba and Punica granatum against Haemonchus contortus
المؤلفون المشاركون
Huluka, Solomon Assefa
Ejo, Mebrat
Mummed, Bahar
Ahmed, Aliyi Hassen
Feyera, Teka
Regassa, Dereje
المصدر
Journal of Parasitology Research
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Gastrointestinal nematodes (GINs) are the major limiting factor for the successfulness of livestock production throughout the world.
Emergence of resistance strains as well as scarcity and high cost of the currently available drugs has led to the evaluation of other alternative helminth control options, mainly from plants.
The current study is aimed at investigating the in vitro anthelmintic efficacy of crude methanolic extracts of two traditionally important medicinal plants, Artemisia herba-alba and Punica granatum, against Haemonchus contortus using adult motility assay (AMA) and egg hatch inhibition assay (EHIA).
Four graded concentrations of the extracts were tested for both the AMA (10, 5, 2.5, and 1.25 mg/mg) and EHIA (0.1, 0.25, 0.5, and 1 mg/mL) in replicates.
Albendazole and phosphate-buffered saline (AMA) or distilled water (EHIA) were used as the positive and negative controls, respectively.
The crude extracts of A.
herba-alba and P.
granatum exhibited a potential anthelmintic activity at all dose levels in a concentration- and time-dependent fashion.
The highest concentration (10 mg/mL) of all the extracts caused a significantly (p<0.05) superior nematocidal activity compared to the negative control.
Moreover, significant and concentration-dependent egg hatching inhibition effect was observed from both plant extracts.
Maximal (98.67%) egg hatching inhibition effect was exhibited by the flower extract of A.
herba-alba at 1 mg/mL concentration.
The relative egg hatch inhibition efficacy indicated that both plants caused a significantly (p<0.05) greater egg hatch inhibition within 48 hr of exposure.
The current study validated the traditional use of both plants as a natural anthelmintic against H.
contortus justifying a need to undertake detail pharmacological and toxicological investigation on both plants.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ahmed, Aliyi Hassen& Ejo, Mebrat& Feyera, Teka& Regassa, Dereje& Mummed, Bahar& Huluka, Solomon Assefa. 2020. In Vitro Anthelmintic Activity of Crude Extracts of Artemisia herba-alba and Punica granatum against Haemonchus contortus. Journal of Parasitology Research،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1190082
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ahmed, Aliyi Hassen…[et al.]. In Vitro Anthelmintic Activity of Crude Extracts of Artemisia herba-alba and Punica granatum against Haemonchus contortus. Journal of Parasitology Research No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1190082
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ahmed, Aliyi Hassen& Ejo, Mebrat& Feyera, Teka& Regassa, Dereje& Mummed, Bahar& Huluka, Solomon Assefa. In Vitro Anthelmintic Activity of Crude Extracts of Artemisia herba-alba and Punica granatum against Haemonchus contortus. Journal of Parasitology Research. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1190082
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1190082
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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