Comparative Analysis of Acral Melanoma in Chinese and Caucasian Patients
المؤلفون المشاركون
Misra, Subhasis
Huang, Kai
Xu, Yu
Gabriel, Emmanuel M.
Chen, Yong
Bagaria, Sanjay P.
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-06
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Acral melanoma (AM) is a rare subtype of melanoma, which is one of the least common in Caucasian patients but is a common subtype of melanoma in Chinese patients.
It is unclear if prognosis differs between Chinese and Caucasian patients diagnosed with AM.
The aim of our study is to investigate patient characteristics and survival differences between Chinese and Caucasian AM patients.
Methods.
Two large institutional melanoma databases from Fudan University Shanghai Cancer Center (FUSCC) and Mayo Clinic enterprise were retrospectively reviewed from 2009 to 2015.
Clinicopathologic and survival data were collected and analyzed between the two groups.
The primary outcome was disease-specific survival (DSS) and was calculated using the Kaplan Meier (KM) method.
Results.
The Chinese group presented with more advanced disease compared with Caucasians: thicker Breslow depth (median 3.0 mm vs.
1.2 mm, p=0.003), more ulcerated disease (66.1% vs.
29%; p<0.001), and advanced stages (stage II/III 84.3% vs.
37.1%; p<0.001).
No significant difference was identified in terms of age at diagnosis, location, histologic subtypes, or node positive rate.
The 5-year DSS rate was 68.4% and 73% (p=0.56) in Chinese and Caucasians AM patients, respectively.
Male gender, Breslow thickness, ulceration, and positive sentinel lymph nodes were independent poor prognostic factors on multivariate analysis.
Conclusions.
There appears to be no difference in stage-stratified survival between Chinese and Caucasians, supporting the implementation of clinical trials for AM that could include both Chinese and Caucasian patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Kai& Xu, Yu& Gabriel, Emmanuel M.& Misra, Subhasis& Chen, Yong& Bagaria, Sanjay P.. 2020. Comparative Analysis of Acral Melanoma in Chinese and Caucasian Patients. Journal of Skin Cancer،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1190738
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Kai…[et al.]. Comparative Analysis of Acral Melanoma in Chinese and Caucasian Patients. Journal of Skin Cancer No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1190738
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Kai& Xu, Yu& Gabriel, Emmanuel M.& Misra, Subhasis& Chen, Yong& Bagaria, Sanjay P.. Comparative Analysis of Acral Melanoma in Chinese and Caucasian Patients. Journal of Skin Cancer. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1190738
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1190738
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر