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How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies
المؤلفون المشاركون
Sebastian, Agata
Sebastian, Maciej
Misterska-Skóra, Maria
Woytala, Patryk
Jakuszko, Katarzyna
Wiland, Piotr
المصدر
Journal of Immunology Research
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
In the course of pSS, inflammatory cell infiltration consists mainly of lymphocytes infiltrating exocrine glands, which leads to their impaired function.
The characteristic feature is generalized dryness.
The aim of this study was to attempt to answer the question whether it is possible to distinguish between patients with pSS and individuals with dryness caused by other pathologies without applying invasive studies.
The study included 68 patients with pSS and 43 healthy controls with dryness.
FS ≥ 1 was observed in 90% of patients with pSS (with or without dryness), and only in 23% of the control group (only with xerostomia).
In the pSS group, anaemia (p=0.0085), lymphocytopenia (p=0.0006), elevated ERS (p=0.001), higher RF titer, and ANA antibodies were noted.
Configuration of anti-SSA + SSB + Ro52 antibodies was characteristic for the pSS group.
Considering the clinical symptoms, statistically significant differences were noted between pSS patients and the control group in frequency (p=0.02) and severity (p=0.042) of fatigue, lymphadenopathy, major salivary gland involvement, and photosensitivity to UV light.
In conclusion, invasive methods are pivotal in pSS diagnosis in this salivary gland biopsy.
Chronic fatigue syndrome is more common in pSS patients and can be subjective distinguishing factor in the group of people with dryness.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sebastian, Agata& Sebastian, Maciej& Misterska-Skóra, Maria& Woytala, Patryk& Jakuszko, Katarzyna& Wiland, Piotr. 2018. How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1191522
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sebastian, Agata…[et al.]. How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies. Journal of Immunology Research No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1191522
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sebastian, Agata& Sebastian, Maciej& Misterska-Skóra, Maria& Woytala, Patryk& Jakuszko, Katarzyna& Wiland, Piotr. How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1191522
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1191522
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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