Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients
المؤلفون المشاركون
Daimiel, Lidia
Vargas, Juan A.
Martínez, J. Alfredo
Martinez-Urbistondo, Maria
Mora-Vargas, Alberto
Expósito-Palomo, Esther
Castejón, Raquel
Citores, M. Jesús
Rosado, Silvia
de Mendoza, Carmen
Baños, Isolina
Fernández-Cruz, Ana
San-Cristóbal, Rodrigo
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) infection elicits inflammatory manifestations that relate with a “cytokine storm.” Objective.
The aim of this research was to assess the role of circulating interleukin 6 (IL-6) levels and other inflammatory markers in patients with coronavirus disease 2019 (COVID-19) on metabolic functions and accompanying clinical complications.
Patients and Methods.
A total of 165 patients diagnosed with COVID-19 pneumonia were examined for medical features and inflammatory markers such as blood IL-6, CRP, ferritin, LDH, neutrophil/lymphocyte index (NLI), D-Dimer, and Red Cell Distribution Width (RDW).
Regression analyses concerning electronically collected medical data were adjusted by appropriate factors and confounding variables.
Results.
Plasma IL-6 determinations evidenced a consistent association with hospital stay days, Intensive Care Unit (ICU) admission, and mortality rates.
Similar trends were found for other proinflammatory variables, where ferritin and NLI showed a remarkable value as surrogates.
Hyperglycaemia and the Charlson Comorbidity Index Score were positively associated with the inflammatory response induced by the SARS-COV-2 infection.
An unhealthy lifestyle such as smoking and alcoholic drinks consumption as well as excessive body adiposity influenced inflammatory-related outcomes in the screened patients.
Conclusion.
IL-6 together with other inflammatory biomarkers accompanied poor clinical and metabolic outcomes in COVID-19-infected patients.
IL-6 may result in a suitable proxy to individually categorise patients in order to manage this infectious pandemic.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Martinez-Urbistondo, Maria& Mora-Vargas, Alberto& Expósito-Palomo, Esther& Castejón, Raquel& Citores, M. Jesús& Rosado, Silvia…[et al.]. 2020. Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1191616
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Martinez-Urbistondo, Maria…[et al.]. Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients. Mediators of Inflammation No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1191616
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Martinez-Urbistondo, Maria& Mora-Vargas, Alberto& Expósito-Palomo, Esther& Castejón, Raquel& Citores, M. Jesús& Rosado, Silvia…[et al.]. Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1191616
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1191616
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر