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The Enlargement of Abdominal Lymph Nodes Is a Characteristic of Autoimmune Liver Disease
المؤلفون المشاركون
Wang, Yongjuan
Guo, Xiaopei
Zhou, Lu
Zhang, Jie
Wang, Bangmao
Xu, Xiuxiu
Ran, Maojuan
Wang, Xi
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The enlargement of lymph nodes is a common clinical sign in connective tissue disease (CTD) and viral hepatitis.
In this research, we evaluated the incidence of enlarged lymph nodes in autoimmune liver diseases (AILD).
Moreover, we identified the clinical significance of abdominal lymph node enlargement in AILD.
Methods.
The characteristics of abdominal lymph nodes, including their morphology and distribution, were assessed by ultrasonography and computed tomography in 125 patients with AILD, 54 with viral hepatitis, 135 with CTD, and 80 healthy controls.
The pathological and laboratory results of 106 AILD patients were collected to analyze the association between lymphadenectasis and disease activity.
Results.
Enlargement of abdominal lymph nodes was found in 69.6% of patients with AILD, 63% of patients with viral hepatitis, 29.6% of patients with CTD, and 2% of healthy controls.
Alkaline phosphatase (ALP), glutamate transpeptidase (GGT), and immunoglobulin M (IgM) levels were significantly increased in AILD patients with lymphadenectasis (LA) in contrast to patients without lymphadenectasis (NLA) (P<0.05).
The pathological characteristics of inflammation, cholestasis, and focal necrosis were more common in the LA group than in the NLA group (P<0.05).
As shown by multivariate logistic regression analysis, interface hepatitis (OR=3.651, P<0.05), cholestasis (OR=8.137, P<0.05), and focal necrosis (OR=5.212, P<0.05) were related to LA.
Conclusions.
The percentage of abdominal lymph node enlargement in AILD subjects was significantly higher than that in CTD subjects.
Therefore, the enlargement of lymph nodes can represent a noninvasive indicator of histological and biochemical inflammation activity in AILD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Yongjuan& Xu, Xiuxiu& Ran, Maojuan& Guo, Xiaopei& Zhou, Lu& Wang, Xi…[et al.]. 2020. The Enlargement of Abdominal Lymph Nodes Is a Characteristic of Autoimmune Liver Disease. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1191684
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Yongjuan…[et al.]. The Enlargement of Abdominal Lymph Nodes Is a Characteristic of Autoimmune Liver Disease. Mediators of Inflammation No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1191684
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Yongjuan& Xu, Xiuxiu& Ran, Maojuan& Guo, Xiaopei& Zhou, Lu& Wang, Xi…[et al.]. The Enlargement of Abdominal Lymph Nodes Is a Characteristic of Autoimmune Liver Disease. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1191684
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1191684
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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