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Fatty Acid Profile and Metabolism Are Related to Human Sperm Parameters and Are Relevant in Idiopathic Infertility and Varicocele
المؤلفون المشاركون
Collodel, Giulia
Moretti, Elena
Noto, Daria
Iacoponi, Francesca
Signorini, Cinzia
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-31
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Objectives.
Fatty acids (FA) modulate oxidative stress, reactive oxygen species (ROS) production, and inflammatory processes in spermatogenesis.
Methods.
The amount of 17 different FAs and the level of F2-isoprostanes (F2-IsoPs) and cytoplasmic phospholipase A2 (cPLA2) were compared and correlated to sperm characteristics; these last ones were evaluated by light and electronic microscopy in varicocele and idiopathic infertile patients.
Results.
Total n-3 polyunsaturated acids (PUFAs) and docosahexaenoic acid (DHA), one of the n-3 PUFAs, were significantly reduced in idiopathic infertile men compared to controls (P<0.05).
In the whole studied population, oleic acid and total monounsaturated acids (MUFAs) correlated negatively with sperm concentration, progressive motility, normal morphology, vitality, and fertility index and positively with sperm necrosis.
Eicosapentaenoic acid (EPA) amount was positively correlated with the percentage of sperm necrosis and cPLA2 level and negatively with sperm concentration.
Sperm vitality was negatively correlated with the saturated fatty acids (SFAs).
In infertile groups, cPLA2 was negatively correlated with DHA and n-3 PUFAs (both P<0.05) and positively with EPA (P<0.05).
In the varicocele group, sperm vitality was negatively correlated with palmitoleic acid and total n-6 PUFAs (P<0.05); sperm apoptosis was positively correlated with the total SFA percentage (P<0.05).
Conclusions.
FA composition in sperm membrane and the metabolism of sperm FAs are interrelated parameters, both relevant in sperm maturation processes and fertility.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Collodel, Giulia& Moretti, Elena& Noto, Daria& Iacoponi, Francesca& Signorini, Cinzia. 2020. Fatty Acid Profile and Metabolism Are Related to Human Sperm Parameters and Are Relevant in Idiopathic Infertility and Varicocele. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1191685
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Collodel, Giulia…[et al.]. Fatty Acid Profile and Metabolism Are Related to Human Sperm Parameters and Are Relevant in Idiopathic Infertility and Varicocele. Mediators of Inflammation No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1191685
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Collodel, Giulia& Moretti, Elena& Noto, Daria& Iacoponi, Francesca& Signorini, Cinzia. Fatty Acid Profile and Metabolism Are Related to Human Sperm Parameters and Are Relevant in Idiopathic Infertility and Varicocele. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1191685
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1191685
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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