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Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation
المؤلفون المشاركون
Casolaro, Vincenzo
Selleri, Carmine
Salzano, Francesco Antonio
Marino, Luigi
Salzano, Giovanni
Botta, Riccardo Maria
Cascone, Giovanni
D’Agostino Fiorenza, Umberto
المصدر
Journal of Immunology Research
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-03
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
The prevalence of reactive nasal inflammatory conditions, for example, allergic rhinitis and chronic rhinosinusitis, is steadily increasing in parallel with significant environmental changes worldwide.
Allergens and as yet undefined environmental agents may trigger these conditions via the involvement of host intrinsic factors, including the innate and adaptive immune system, the nasal epithelium, and the nasal nervous system.
The critical role of the nasal microbiota in coordinating these components has emerged in recent studies documenting a significant association between microbial composition and the onset and progression of allergic or nonallergic inflammation.
It is now clear that the local microbiota is a major player in the development of the mucosa-associated lymphoid tissue and in the regulation of such adaptive responses as IgA production and the function of effector and regulatory T cells.
Microbial components also play a major role in the regulation of epithelial barrier functions, including mucus production and the control of paracellular transport across tight junctions.
Bacterial components, including lipopolysaccharide, have also been shown to induce or amplify neuroinflammatory responses by engaging specific nociceptors.
Finally, bacterial products may promote tissue remodeling processes, including nasal polyp formation, by interacting with formyl peptide receptors and inducing the expression of angiogenic factors and matrix-degrading enzymes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salzano, Francesco Antonio& Marino, Luigi& Salzano, Giovanni& Botta, Riccardo Maria& Cascone, Giovanni& D’Agostino Fiorenza, Umberto…[et al.]. 2018. Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1191927
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salzano, Francesco Antonio…[et al.]. Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation. Journal of Immunology Research No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1191927
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salzano, Francesco Antonio& Marino, Luigi& Salzano, Giovanni& Botta, Riccardo Maria& Cascone, Giovanni& D’Agostino Fiorenza, Umberto…[et al.]. Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1191927
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1191927
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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