Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study
المؤلفون المشاركون
Zhou, Hou-De
Tang, Hao-Neng
Xiao, Fen
Chen, Ya-Ru
Zhuang, Si-Qi
Guo, Yue
Wu, Hui-Xuan
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-04
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Neuropeptide Y (NPY), an orexigenic peptide known to cause hyperphagia, has been involved in the occurrence and development of obesity.
However, differences in the distribution of serum NPY levels in obese phenotypes (including metabolically unhealthy obesity (MUO) phenotype and metabolically healthy obesity (MHO) phenotype) and the association of NPY with MUO phenotype have not been unequivocally established.
We therefore determined associations of serum NPY levels with MUO phenotype in obese Chinese adults.
Methods.
A cross-sectional study was conducted from 400 obese adults in Hunan province, who underwent a health examination in the Second Xiangya Hospital, and 164 participants were finally enrolled in the study and divided into MHO and MUO groups.
Serum NPY levels were examined; univariate and multivariate analyses as well as smooth curve fitting analyses were conducted to measure the association of NPY serum levels with the MUO phenotype.
Results.
Serum NPY levels were significantly elevated in the MUO group compared with the MHO group ((667.69±292.90) pg/mL vs.
(478.89±145.53) pg/mL, p<0.001).
A threshold and nonlinear association between serum NPY levels and MUO was found (p=0.001).
When serum NPY levels exceeded the turning point (471.5 pg/mL), each 10 pg/mL increment in the NPY serum level was significantly associated with an 18% increased odds ratio of MUO phenotype (OR: 1.18, 95% CI: 1.07–1.29, p=0.0007) after adjusted for confounders.
Conclusions.
Higher NPY serum levels were positively correlated with MUO phenotype in obese Chinese adults.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tang, Hao-Neng& Xiao, Fen& Chen, Ya-Ru& Zhuang, Si-Qi& Guo, Yue& Wu, Hui-Xuan…[et al.]. 2020. Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1192001
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tang, Hao-Neng…[et al.]. Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study. Mediators of Inflammation No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1192001
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tang, Hao-Neng& Xiao, Fen& Chen, Ya-Ru& Zhuang, Si-Qi& Guo, Yue& Wu, Hui-Xuan…[et al.]. Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1192001
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1192001
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر