Interleukin-17: Potential Target for Chronic Wounds
المؤلفون المشاركون
Hadian, Yasmin
Bagood, Michelle D.
Dahle, Sara E.
Sood, Apra
Isseroff, R. Rivkah
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-18
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Chronic wounds exhibit persistent inflammation with markedly delayed healing.
The significant burden of chronic wounds, which are often resistant to standard therapy, prompts further research on novel therapies.
Since the interleukin-17 family has been implicated as a group of proinflammatory cytokines in immune-mediated diseases in the gut and connective tissue, as well as inflammatory skin conditions, we consider here if it may contribute to the pathogenesis of chronic wounds.
In this review, we discuss the interleukin-17 family’s signaling pathways and role in tissue repair.
A PubMed review of the English literature on interleukin-17, wound healing, chronic wounds, and inflammatory skin conditions was conducted.
Interleukin-17 family signaling is reviewed in the context of tissue repair, and preclinical and clinical studies examining its role in the skin and other organ systems are critically reviewed.
The published work supports a pathologic role for interleukin-17 family members in chronic wounds, though this needs to be more conclusively proven.
Clinical studies using monoclonal interleukin-17 antibodies to improve healing of chronic skin wounds have not yet been performed, and only a few studies have examined interleukin-17 family expression in chronic skin wounds.
Furthermore, different interleukin-17 family members could be playing selective roles in the repair process.
These studies suggest a therapeutic role for targeting interleukin-17A to promote wound healing; therefore, interleukin-17A may be a target worthy of pursuing in the near future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hadian, Yasmin& Bagood, Michelle D.& Dahle, Sara E.& Sood, Apra& Isseroff, R. Rivkah. 2019. Interleukin-17: Potential Target for Chronic Wounds. Mediators of Inflammation،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1192579
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hadian, Yasmin…[et al.]. Interleukin-17: Potential Target for Chronic Wounds. Mediators of Inflammation No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1192579
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hadian, Yasmin& Bagood, Michelle D.& Dahle, Sara E.& Sood, Apra& Isseroff, R. Rivkah. Interleukin-17: Potential Target for Chronic Wounds. Mediators of Inflammation. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1192579
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1192579
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر