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Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells
المؤلفون المشاركون
Baos, Selene
Cremades-Jimeno, L.
Cárdaba, Blanca
Calzada, David
المصدر
Journal of Immunology Research
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The immune system regulates itself to establish an appropriate immune response to potentially harmful pathogens while tolerating harmless environmental antigens and self-antigens.
A central role in this balance is played by regulatory T cells (Tregs) through various ways of actions.
By means of molecule secretion and cell-cell contact mechanisms, Tregs may have the capacity to modulate effector T cells and suppress the action of proinflammatory cytokines across a broad range of cell types.
As a result, abnormal regulatory T cell function has been pointed as a main cause in the development of allergic diseases, a major public health problem in industrialized countries, with a high socioeconomic impact.
This prevalence and impact have created an international interest in improving the allergy diagnosis and therapy.
Additionally, research has sought to gain a better understanding of the molecular mechanisms underlining this kind of disease, in order to a better management.
At this respect, the role of Treg cells is one of the most promising areas of research, mainly because of their potential use as new immunotherapeutical approaches.
Therefore, the aim of this review is to update the existing knowledge of the role of Tregs in this pathology deepening in their implication in allergen-specific therapy (AIT).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Calzada, David& Baos, Selene& Cremades-Jimeno, L.& Cárdaba, Blanca. 2018. Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1192683
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Calzada, David…[et al.]. Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells. Journal of Immunology Research No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1192683
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Calzada, David& Baos, Selene& Cremades-Jimeno, L.& Cárdaba, Blanca. Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1192683
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1192683
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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