Could LC-NE-Dependent Adjustment of Neural Gain Drive Functional Brain Network Reorganization?
المؤلفون المشاركون
Guedj, Carole
Meunier, David
Meunier, Martine
Hadj-Bouziane, Fadila
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-21
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The locus coeruleus-norepinephrine (LC-NE) system is thought to act at synaptic, cellular, microcircuit, and network levels to facilitate cognitive functions through at least two different processes, not mutually exclusive.
Accordingly, as a reset signal, the LC-NE system could trigger brain network reorganizations in response to salient information in the environment and/or adjust the neural gain within its target regions to optimize behavioral responses.
Here, we provide evidence of the co-occurrence of these two mechanisms at the whole-brain level, in resting-state conditions following a pharmacological stimulation of the LC-NE system.
We propose that these two mechanisms are interdependent such that the LC-NE-dependent adjustment of the neural gain inferred from the clustering coefficient could drive functional brain network reorganizations through coherence in the gamma rhythm.
Via the temporal dynamic of gamma-range band-limited power, the release of NE could adjust the neural gain, promoting interactions only within the neuronal populations whose amplitude envelopes are correlated, thus making it possible to reorganize neuronal ensembles, functional networks, and ultimately, behavioral responses.
Thus, our proposal offers a unified framework integrating the putative influence of the LC-NE system on both local- and long-range adjustments of brain dynamics underlying behavioral flexibility.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guedj, Carole& Meunier, David& Meunier, Martine& Hadj-Bouziane, Fadila. 2017. Could LC-NE-Dependent Adjustment of Neural Gain Drive Functional Brain Network Reorganization?. Neural Plasticity،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1193012
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guedj, Carole…[et al.]. Could LC-NE-Dependent Adjustment of Neural Gain Drive Functional Brain Network Reorganization?. Neural Plasticity No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1193012
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guedj, Carole& Meunier, David& Meunier, Martine& Hadj-Bouziane, Fadila. Could LC-NE-Dependent Adjustment of Neural Gain Drive Functional Brain Network Reorganization?. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1193012
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1193012
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر