Abundance of Gut Microbiota, Concentration of Short-Chain Fatty Acids, and Inflammatory Markers Associated with Elevated Body Fat, Overweight, and Obesity in Female Adolescents
المؤلفون المشاركون
Priore, Silvia Eloiza
Peluzio, Maria do Carmo Gouveia
Miranda, Valter Paulo Neves
dos Santos Amorim, Paulo Roberto
Bastos, Ronaldo Rocha
do Carmo Castro Franceschini, Sylvia
de Faria, Eliane Rodrigues
de Castro Moreira, Maria Eliza
de Luces Fortes Ferreira, Célia Lucia
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-17
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background and Aims.
Overweight is ever more prevalent in the pediatric population, and this cardiometabolic factor can be associated with inflammatory markers, gut microbiota composition, and short-chain fatty acid (SCFA) concentrations.
The aim of this study is to evaluate to what extent the abundance of gut microbiota phyla, SCFA concentrations, and inflammatory markers are associated with elevated body fat percentage (BF%), overweight, and obesity in female adolescents.
Methods.
An experimental and comparative study was conducted with 96 girls 14 to 19 years old.
They were divided into 3 groups: G1—eutrophic (EUT) and adequate BF%; G2—EUT and high BF%; and G3—overweight (OW) or obese (OB) and high BF%.
Waist circumference (WC), waist to height ratio (WtHR), and neck circumference (NC) were analyzed as indicators of central visceral adiposity.
The BF% was evaluated by DEXA equipment.
A food frequency questionnaire was used to evaluate the main types of food consumed in a week.
The abundance of the Firmicutes, Bacteroidetes, and Proteobacteria phyla was measured by real-time polymerase chain reaction (RT-qPCR), and the SFCA concentrations (acetic, butyric, and propionic) were determined by high-performance liquid chromatography (HPLC).
The inflammatory markers leptin, tumor necrosis factor-alpha, interleukin-6, and high-sensitivity C-reactive protein (hs-CRP) were assessed.
Results.
Female adolescents in groups G2 and G3 had greater central visceral adiposity and leptin concentration than those in group G1.
No association was found between gut microbiota phyla abundance and SFCA concentrations in any of the groups.
WC and frequency of consumption of oily and fatty foods were associated with Firmicutes abundance and SFCA concentrations.
Girls with high WC also had the greatest leptin (p<0.001) and hs-CRP (p=0.035) concentrations.
Conclusions.
Inflammatory markers showed association with increased BMI and high BF% in female adolescents.
The abundance of Firmicutes was associated with WC and NC, but not with BMI classification or BF%.
Specifically, WC and the consumption of oils and fats showed correlation with SCFA concentrations.
Different anthropometric indicators, such as NC and WC, should be incorporated into the clinical evaluation of the nutritional status of individuals in the adolescent population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Miranda, Valter Paulo Neves& dos Santos Amorim, Paulo Roberto& Bastos, Ronaldo Rocha& de Faria, Eliane Rodrigues& de Castro Moreira, Maria Eliza& do Carmo Castro Franceschini, Sylvia…[et al.]. 2019. Abundance of Gut Microbiota, Concentration of Short-Chain Fatty Acids, and Inflammatory Markers Associated with Elevated Body Fat, Overweight, and Obesity in Female Adolescents. Mediators of Inflammation،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1193260
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Miranda, Valter Paulo Neves…[et al.]. Abundance of Gut Microbiota, Concentration of Short-Chain Fatty Acids, and Inflammatory Markers Associated with Elevated Body Fat, Overweight, and Obesity in Female Adolescents. Mediators of Inflammation No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1193260
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Miranda, Valter Paulo Neves& dos Santos Amorim, Paulo Roberto& Bastos, Ronaldo Rocha& de Faria, Eliane Rodrigues& de Castro Moreira, Maria Eliza& do Carmo Castro Franceschini, Sylvia…[et al.]. Abundance of Gut Microbiota, Concentration of Short-Chain Fatty Acids, and Inflammatory Markers Associated with Elevated Body Fat, Overweight, and Obesity in Female Adolescents. Mediators of Inflammation. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1193260
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1193260
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر