Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer
المؤلفون المشاركون
Gasbarrini, Antonio
Cammarota, G.
Milella, Michele
Carbone, Carmine
Piro, Geny
Di Noia, Vincenzo
D’Argento, Ettore
Vita, Emanuele
Ferrara, Miriam Grazia
Pilotto, Sara
Tortora, Giampaolo
Bria, Emilio
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Lung cancer is one of the deadliest and most common malignancies in the world, representing one of the greatest challenges in cancer treatment.
Immunotherapy is rapidly changing standard treatment schedule and outcomes for patients with advanced malignancies.
However, several ongoing studies are still attempting to elucidate the biomarkers that could predict treatment response as well as the new strategies to improve antitumor immune system response ameliorating immunotherapy efficacy.
The complex of bacteria, fungi, and other microorganisms, termed microbiota, that live on the epithelial barriers of the host, are involved in the initiation, progression, and dissemination of cancer.
The functional role of microbiota has attracted an accumulating attention recently.
Indeed, it has been demonstrated that commensal microorganisms are required for the maturation, education, and function of the immune system regulating the efficacy of immunotherapy in the anticancer response.
In this review, we discuss some of the major findings depicting bacteria as crucial gatekeeper for the immune response against tumor and their role as driver of immunotherapy efficacy in lung cancer with a special focus on the distinctive role of gut and lung microbiota in the efficacy of immunotherapy treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Carbone, Carmine& Piro, Geny& Di Noia, Vincenzo& D’Argento, Ettore& Vita, Emanuele& Ferrara, Miriam Grazia…[et al.]. 2019. Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer. Mediators of Inflammation،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1193308
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Carbone, Carmine…[et al.]. Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer. Mediators of Inflammation No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1193308
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Carbone, Carmine& Piro, Geny& Di Noia, Vincenzo& D’Argento, Ettore& Vita, Emanuele& Ferrara, Miriam Grazia…[et al.]. Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer. Mediators of Inflammation. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1193308
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1193308
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر