Magnesium Oxide in Nanodimension: Model for MRI and Multimodal Therapy
المؤلفون المشاركون
Fakhar-e-Alam, Muhammad
Wang, Zhiming M.
Iqbal, Seemab
Alimgeer, Khurram Saleem
Akram, Muhammad Waseem
Butt, Alvina Rafiq
Munir, T.
Ali, Akbar
Mehmood-ur-Rehman, Khalid
Ali, Salamat
Ikram, Muhammad
Amin, N.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-20
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The prime focus of this investigation is to determine which morphology of magnesium oxide (MgO) is nontoxic and accumulates in sufficient quantity to a human brain cellular/tissue model.
Thus, nanostructured MgO was synthesized from a coprecipitation technique involving twin synthetic protocols and the resulting product was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), size distribution histogram, Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) analysis and elemental composition was confirmed by EDX analysis.
They were tested for selective antigen response in a human brain cancer model through biodistribution, biotoxicity via MTT assay, and tissue morphology.
In addition, the MRI compatibility of MgO nanostructures and immunofluorescence studies were investigated on nanoconjugates with different immunoglobulins in the brain section.
The results indicated that MgO had some degree of bindings with the antigens.
These results led to the empirical modeling of MgO nanomaterials towards toxicity in cancer cells by analyzing the statistical data obtained by experiments.
All these results are providing new rational strategy with the concept of MgO for MRI and PTT/PDT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Akram, Muhammad Waseem& Fakhar-e-Alam, Muhammad& Butt, Alvina Rafiq& Munir, T.& Ali, Akbar& Alimgeer, Khurram Saleem…[et al.]. 2018. Magnesium Oxide in Nanodimension: Model for MRI and Multimodal Therapy. Journal of Nanomaterials،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1194101
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Akram, Muhammad Waseem…[et al.]. Magnesium Oxide in Nanodimension: Model for MRI and Multimodal Therapy. Journal of Nanomaterials No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1194101
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Akram, Muhammad Waseem& Fakhar-e-Alam, Muhammad& Butt, Alvina Rafiq& Munir, T.& Ali, Akbar& Alimgeer, Khurram Saleem…[et al.]. Magnesium Oxide in Nanodimension: Model for MRI and Multimodal Therapy. Journal of Nanomaterials. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1194101
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1194101
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر