Spondias purpurea L. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract
المؤلفون المشاركون
Silva, Márcia Vanusa da
Santos, Vanda L.
Rolim, Larissa Araújo
Júnior, Carlson H. R. C.
de Almeida, Cynthia Layse Ferreira
Brito, Samara Alves
de Santana, Temístocles Italo
Costa, Henrique Bandeira Alves
de Almeida, Lécio Leone
Wanderley, Almir Gonçalves
da Silva, Teresinha Gonçalves
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-26
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Spondias purpurea is used in folk medicine to treat diarrhea and diuresis.
The objective of this study was to evaluate the phytochemical profile and antioxidant and antiulcer activities of the hexane extract of the leaves of S.
purpurea (SpHE).
Phytochemical profile was evaluated via thin layer chromatography (TLC) and HPLC.
SpHE was screened for antioxidant activities using DPPH, ABTS, FRAP, and phosphomolybdenum assays.
To determine its antiulcer properties, animals were pretreated with injured control, lansoprazole, ranitidine, carbenoxolone, or SpHE (12.5, 25, and 50 mg/kg) and were screened; acute ulcers were induced by HCl/ethanol, absolute ethanol, and nonsteroidal anti-inflammatory drug (NSAID).
TLC revealed the presence of flavonoids, whereas HPLC analysis showed the presence of caffeic acid and epigallocatechin.
The phenolic compounds and in vitro assays showed antioxidant activity.
After gastric ulcer induction by using HCl/ethanol, SpHE reduced the area of ulcerative lesions by 82, 91, and 88%, respectively.
In ethanol, SpHE reduced the area of ulcerative lesions by 77, 93, and 92%, respectively.
In the NSAID, the percentages of protection were 70, 76, and 78%, respectively.
SpHE promoted the minimization of ulcers, increased the levels of reduced glutathione, and decreased tumor necrosis factor.
S.
purpurea has antioxidant and antiulcer properties.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Almeida, Cynthia Layse Ferreira& Brito, Samara Alves& de Santana, Temístocles Italo& Costa, Henrique Bandeira Alves& Júnior, Carlson H. R. C.& Silva, Márcia Vanusa da…[et al.]. 2017. Spondias purpurea L. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1195277
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Almeida, Cynthia Layse Ferreira…[et al.]. Spondias purpurea L. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1195277
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Almeida, Cynthia Layse Ferreira& Brito, Samara Alves& de Santana, Temístocles Italo& Costa, Henrique Bandeira Alves& Júnior, Carlson H. R. C.& Silva, Márcia Vanusa da…[et al.]. Spondias purpurea L. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1195277
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1195277
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر