Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine
المؤلفون المشاركون
Kneisl, Jeffrey S.
Alamanda, Vignesh K.
Robinson, Myra M.
Spector, Leo R.
Patt, Joshua C.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Study Design.
Retrospective review of a prospective database.
Objective.
Certain subset of patients undergoing surgical treatment for spinal metastasis will require a revision surgery in their disease course; however, factors predictive of revision surgery and survival outcomes are largely unknown.
The goal of this study is to report on survival outcomes as well as factors predictive of revision surgery in this unique patient population.
Methods.
A total of 55 patients who met the inclusion criteria were included from January 2010 to December 2015.
Twelve (22%) of these patients underwent a revision surgery.
Patient and tumor characteristics were summarized and survival outcomes were evaluated using Kaplan-Meier methods and Cox proportional hazards regression.
Results.
Both the revision and the nonrevision groups were similarly matched with respect to spine disease burden, neurological status at time of initial presentation, primary malignancy types, and the use of adjuvant treatment modalities.
Tumor progression (66.7%) was the most common reason for necessitating a revision followed by nonunion (16.7%), wound dehiscence (8.3%), and construct failure (8.3%).
Following multivariate model selection procedures, smokers were found to have 3.5 times increased odds of undergoing revision compared to nonsmokers (p = 0.05).
Analysis of survival curves showed that the median survival in the revision group was 3.0 years (95% CI: 1.5, 4.1), while the median survival in the nonrevision group was 1.5 years (95% CI: 1.1, 2.3; log-rank test, p = 0.105).
Conclusion.
Despite aggressive treatment, tumor progression is the most common reason for revision surgery.
Smoking is an independent risk factor for revision.
Revision surgery should be considered in patients when indicated as it does not appear to detrimentally affect survival.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alamanda, Vignesh K.& Robinson, Myra M.& Kneisl, Jeffrey S.& Spector, Leo R.& Patt, Joshua C.. 2018. Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine. Journal of Oncology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1195813
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alamanda, Vignesh K.…[et al.]. Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine. Journal of Oncology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1195813
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alamanda, Vignesh K.& Robinson, Myra M.& Kneisl, Jeffrey S.& Spector, Leo R.& Patt, Joshua C.. Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine. Journal of Oncology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1195813
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1195813
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر