HBV-DNA Load-Related Peritumoral Inflammation and ALBI Scores Predict HBV Associated Hepatocellular Carcinoma Prognosis after Curative Resection
المؤلفون المشاركون
Liao, Rui
Du, Cheng-You
Gong, Jian-Ping
Luo, Fang
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-09-20
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Both persistent inflammatory activity and liver function damage contribute to a poor prognosis of hepatocellular carcinoma (HCC).
This study aimed to develop nomograms that incorporate hepatitis virus B (HBV)-related peritumoral inflammation score (PIS) and liver function based on ALBI score to predict postoperative outcomes of HCC.
Methods.
The prognostic roles of HBV-related preoperative PIS and ALBI scores in HCC recurrence were examined, and then two nomograms were constructed.
The predictive accuracy and discriminative ability of the nomograms were compared with AJCC and BCLC staging systems of HCC.
Results.
PIS (HBV-PIS) and ALBI scores (HBV-ALBI) with different HBV-DNA loads had association with overall survival (OS) and/or recurrence-free survival (RFS) of HCC.
The independent predictors of OS and RFS were incorporated into the corresponding nomograms.
In the training cohort, the C-indexes of OS and RFS nomograms were 0.751 and 0.736, respectively.
ROC analyses showed that both OS and RFS nomograms had larger AUC (0.775 and 0.739, respectively) than AJCC and BCLC staging systems.
These results were verified by the internal and external validation cohorts.
Conclusion.
The proposed nomograms, including HBV-DNA load-related PIS and ALBI scores, were accurate in predicting survival for HCC after curative resection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liao, Rui& Du, Cheng-You& Gong, Jian-Ping& Luo, Fang. 2018. HBV-DNA Load-Related Peritumoral Inflammation and ALBI Scores Predict HBV Associated Hepatocellular Carcinoma Prognosis after Curative Resection. Journal of Oncology،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1195880
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liao, Rui…[et al.]. HBV-DNA Load-Related Peritumoral Inflammation and ALBI Scores Predict HBV Associated Hepatocellular Carcinoma Prognosis after Curative Resection. Journal of Oncology No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1195880
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liao, Rui& Du, Cheng-You& Gong, Jian-Ping& Luo, Fang. HBV-DNA Load-Related Peritumoral Inflammation and ALBI Scores Predict HBV Associated Hepatocellular Carcinoma Prognosis after Curative Resection. Journal of Oncology. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1195880
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1195880
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر