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Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro
المؤلفون المشاركون
Feyerabend, Frank
Luthringer, Bérengère
Willumeit, Regine
Liu, Zhidan
Schade, Ronald
Hort, Norbert
Rothe, Holger
Müller, Sören
Liefeith, Klaus
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-22
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Implantation is a frequent procedure in orthopedic surgery, particularly in the aging population.
However, it possesses the risk of infection and biofilm formation at the surgical site.
This can cause unnecessary suffering to patients and burden on the healthcare system.
Pure Mg, as a promising metal for biodegradable orthopedic implants, exhibits some antibacterial effects due to the alkaline pH produced during degradation.
However, this antibacterial effect may not be sufficient in a dynamic environment, for example, the human body.
The aim of this study was to increase the antibacterial properties under harsh and dynamic conditions by alloying silver metal with pure Mg as much as possible.
Meanwhile, the Mg-Ag alloys should not show obvious cytotoxicity to human primary osteoblasts.
Therefore, we studied the influence of the microstructure and the silver content on the degradation behavior, cytocompatibility, and antibacterial properties of Mg-Ag alloys in vitro.
The results indicated that a higher silver content can increase the degradation rate of Mg-Ag alloys.
However, the degradation rate could be reduced by eliminating the precipitates in the Mg-Ag alloys via T4 treatment.
By controlling the microstructure and increasing the silver content, Mg-Ag alloys obtained good antibacterial properties in harsh and dynamic conditions but had almost equivalent cytocompatibility to human primary osteoblasts as pure Mg.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Zhidan& Schade, Ronald& Luthringer, Bérengère& Hort, Norbert& Rothe, Holger& Müller, Sören…[et al.]. 2017. Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1195914
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Zhidan…[et al.]. Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1195914
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Zhidan& Schade, Ronald& Luthringer, Bérengère& Hort, Norbert& Rothe, Holger& Müller, Sören…[et al.]. Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1195914
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1195914
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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