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Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review
المؤلفون المشاركون
Lu, Lei
Jiang, Ying
Hao, Yanli
Jaganathan, Ravindran
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-17
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Diabetic retinopathy (DR) is classically defined by its vascular lesions and damage in the neurons of the retina.
The cellular and clinical elements of DR have many features of chronic inflammation.
Understanding the individual cell-specific inflammatory changes in the retina may lead to novel therapeutic approaches to prevent vision loss.
The systematic use of available pharmacotherapy has been reported as a useful adjunct tool to laser photocoagulation, a gold standard therapy for DR.
Direct injections or intravitreal anti-inflammatory and antiangiogenesis agents are widely used pharmacotherapy to effectively treat DR and diabetic macular edema (DME).
However, their effectiveness is short term, and the delivery system is often associated with adverse effects, such as cataract and increased intraocular pressure.
Further, systemic agents (particularly hypoglycemic, hypolipidemic, and antihypertensive agents) and plants-based drugs have also provided promising treatment in the progression of DR.
Recently, advancements in pluripotent stem cells technology enable restoration of retinal functionalities after transplantation of these cells into animals with retinal degeneration.
This review paper summarizes the developments in the current and potential pharmacotherapy and therapeutic technology of DR.
Literature search was done on online databases, PubMed, Google Scholar, clinitrials.gov, and browsing through individual ophthalmology journals and leading pharmaceutical company websites.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Lei& Jiang, Ying& Jaganathan, Ravindran& Hao, Yanli. 2018. Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1196209
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Lei…[et al.]. Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review. Journal of Ophthalmology No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1196209
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Lei& Jiang, Ying& Jaganathan, Ravindran& Hao, Yanli. Current Advances in Pharmacotherapy and Technology for Diabetic Retinopathy: A Systematic Review. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1196209
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1196209
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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