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Extended Injection Intervals after Switching from Ranibizumab to Aflibercept in Macular Edema due to Central Retinal Vein Occlusion
المؤلفون المشاركون
Cohen, Salomon Yves
Nghiem-Buffet, Sylvia
Giocanti-Auregan, Audrey
Addou-Regnard, Manar
Glacet-Bernard, Agnès
Souied, Eric H.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-15
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
To assess treatment interval extension after switching from ranibizumab to aflibercept intravitreal injections in macular edema (ME) due to central retinal vein occlusion (CRVO) with an insufficient response or frequent recurrences to initial treatment.
Methods.
CRVO eyes treated with ranibizumab injections on a treat-and-extend (TAE) basis with an insufficient response or frequent recurrences were switched to aflibercept.
Primary endpoint was the change in injection intervals before and after the switch.
Results.
Eleven eyes were included in this retrospective bicentric study.
Before switching, patients received a mean number of 15.3 ranibizumab injections (range, 6–34) during a mean follow-up of 23.4 months (range, 6–57).
After switching to aflibercept, patients received a mean number of 12.4 injections (range, 6–20) during a mean follow-up of 25.5 months (range, 16–38).
Treatment interval could be extended from 6.1 (range, 4–8) to 11 weeks (range, 8–16) (p=0.001) corresponding to a mean extension of injection interval of +4.9 weeks.
Conclusion.
In case of insufficient response or frequent recurrences of ME due to CRVO in patients treated with ranibizumab on a TAE basis, switching to aflibercept could allow extending treatment intervals, which could reduce the injection burden for these patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nghiem-Buffet, Sylvia& Glacet-Bernard, Agnès& Addou-Regnard, Manar& Souied, Eric H.& Cohen, Salomon Yves& Giocanti-Auregan, Audrey. 2018. Extended Injection Intervals after Switching from Ranibizumab to Aflibercept in Macular Edema due to Central Retinal Vein Occlusion. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1197034
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nghiem-Buffet, Sylvia…[et al.]. Extended Injection Intervals after Switching from Ranibizumab to Aflibercept in Macular Edema due to Central Retinal Vein Occlusion. Journal of Ophthalmology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1197034
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nghiem-Buffet, Sylvia& Glacet-Bernard, Agnès& Addou-Regnard, Manar& Souied, Eric H.& Cohen, Salomon Yves& Giocanti-Auregan, Audrey. Extended Injection Intervals after Switching from Ranibizumab to Aflibercept in Macular Edema due to Central Retinal Vein Occlusion. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1197034
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1197034
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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