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FRAX Calculated without BMD Resulting in a Higher Fracture Risk Than That Calculated with BMD in Women with Early Breast Cancer
المؤلفون المشاركون
Schwarz, Peter
Helge, E. W.
Prawiradilaga, Rizky Suganda
Gunmalm, Victoria
Lund-Jacobsen, Trine
Brøns, Charlotte
Andersson, Michael
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background (and Purpose).
The aim of this study was to investigate the importance of including the measurement of bone mineral density (BMD) in reliable fracture risk assessment for women diagnosed with early nonmetastatic breast cancer (EBC) before AI treatment if zoledronic acid is not an option.
Material and Methods.
One hundred and sixteen women with EBC were included in the study before initiating AI treatment.
Most participants were osteopenic.
The 10-year probability of hip fracture and major osteoporotic fracture was calculated with and without BMD based on clinical information collected at baseline using the fracture risk assessment (FRAX) tool.
To compare data, the nonparametric tests were used.
Results.
There was a significant difference (p<0.001) in the number of high-risk and low-risk FRAX score of hip fracture between before and after including BMD values.
The high-risk category decreased by 50.9%, while the low-risk category increased by 42.9%.
In FRAX score of major osteoporotic the findings were similar (p<0.001): The high-risk and moderate-risk category decreased by 70.4% and 4.9%, respectively, while the low-risk category increased by 43.8% when including BMD value.
When stratified by age, patients aged 65 years or older were at a significantly (p<0.001) higher risk of suffering a hip or major osteoporotic fracture, highlighting the importance of including BMD measurements in this age group.
Conclusions.
Our data support that DXA scanning of women with EBC should be performed to avoid overestimation of osteoporosis before AI treatment.
It is particularly important in patients older than 65 years of age and when zoledronic acid is not an option.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Prawiradilaga, Rizky Suganda& Gunmalm, Victoria& Lund-Jacobsen, Trine& Helge, E. W.& Brøns, Charlotte& Andersson, Michael…[et al.]. 2018. FRAX Calculated without BMD Resulting in a Higher Fracture Risk Than That Calculated with BMD in Women with Early Breast Cancer. Journal of Osteoporosis،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1197305
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Prawiradilaga, Rizky Suganda…[et al.]. FRAX Calculated without BMD Resulting in a Higher Fracture Risk Than That Calculated with BMD in Women with Early Breast Cancer. Journal of Osteoporosis No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1197305
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Prawiradilaga, Rizky Suganda& Gunmalm, Victoria& Lund-Jacobsen, Trine& Helge, E. W.& Brøns, Charlotte& Andersson, Michael…[et al.]. FRAX Calculated without BMD Resulting in a Higher Fracture Risk Than That Calculated with BMD in Women with Early Breast Cancer. Journal of Osteoporosis. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1197305
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1197305
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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