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Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns
المؤلفون المشاركون
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-23، 23ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-28
دولة النشر
مصر
عدد الصفحات
23
التخصصات الرئيسية
الملخص EN
Preeclampsia (PE) is a disorder which affects 1-10% of pregnant women worldwide.
It is characterised by hypertension and proteinuria in the later stages of gestation and can lead to maternal and perinatal morbidity and mortality.
Other than the delivery of the foetus and the removal of the placenta, to date there are no therapeutic approaches to treat or prevent PE.
It is thus only possible to reduce PE-related mortality through early detection, careful monitoring, and treatment of the symptoms.
For these reasons the search for noninvasive, blood-borne, or urinary biochemical markers that could be used for the screening, presymptomatic diagnosis, and prediction of the development of PE is of great urgency.
So far, a number of biomarkers have been proposed for predicting PE, based on pathophysiological observations, but these have mostly proven to be unreliable and inconsistent between different studies.
The clinical presentation of PE and data gathered for the biochemical markers placental growth factor (PlGF), soluble Feline McDonough Sarcoma- (fms-) like tyrosine kinase-1 (sFlt-1), asymmetric dimethylarginine (ADMA), and methyl-lysine is being reviewed with the aim of providing both a clinical and biochemical understanding of how these biomarkers might assist in the diagnosis of PE or indicate its severity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Portelli, Maria& Baron, Byron. 2018. Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns. Journal of Pregnancy،Vol. 2018, no. 2018, pp.1-23.
https://search.emarefa.net/detail/BIM-1197342
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Portelli, Maria& Baron, Byron. Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns. Journal of Pregnancy No. 2018 (2018), pp.1-23.
https://search.emarefa.net/detail/BIM-1197342
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Portelli, Maria& Baron, Byron. Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns. Journal of Pregnancy. 2018. Vol. 2018, no. 2018, pp.1-23.
https://search.emarefa.net/detail/BIM-1197342
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1197342
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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