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Self-Reported Adverse Drug Reactions, Medication Adherence, and Clinical Outcomes among Major Depressive Disorder Patients in Ethiopia: A Prospective Hospital Based Study
المؤلفون المشاركون
Sori, Lamessa Melese
Abegaz, Tadesse Melaku
Toleha, Hussien Nurahmed
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-14
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
علم النفس
الطب البشري
الطب النفسي
الملخص EN
Background.
There is paucity of data on prevalence of Adverse Drug Reactions (ADRs) and adherence and clinical outcomes of antidepressants.
The present study determined the magnitude of ADRs of antidepressants and their impact on the level of adherence and clinical outcome.
Methods.
A prospective cross-sectional study was conducted among depression patients from September 2016 to January 2017 at Gondar University Hospital psychiatry clinic.
The Naranjo ADR probability scale was employed to assess the ADRs.
The rate of medication adherence was determined using Morisky Medication Adherence Measurement Scale-Eight.
Results.
Two hundred seventeen patients participated in the study, more than half of them being males (122; 56.2%).
More than one-half of the subjects had low adherence to their medications (124; 57.1%) and about 186 (85.7%) of the patients encountered ADR.
The most common ADR was weight gain (29; 13.2%).
More than one-half (125; 57.6%) of the respondents showed improved clinical outcome.
Optimal level of medication adherence decreased the likelihood of poor clinical outcome by 56.8%.
Conclusion.
ADRs were more prevalent.
However, adherence to medications was very poor in the setup.
Long duration of depression negatively affects the rate of adherence.
In addition, adherence was found to influence the clinical outcome of depression patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abegaz, Tadesse Melaku& Sori, Lamessa Melese& Toleha, Hussien Nurahmed. 2017. Self-Reported Adverse Drug Reactions, Medication Adherence, and Clinical Outcomes among Major Depressive Disorder Patients in Ethiopia: A Prospective Hospital Based Study. Psychiatry Journal،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1197598
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abegaz, Tadesse Melaku…[et al.]. Self-Reported Adverse Drug Reactions, Medication Adherence, and Clinical Outcomes among Major Depressive Disorder Patients in Ethiopia: A Prospective Hospital Based Study. Psychiatry Journal No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1197598
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abegaz, Tadesse Melaku& Sori, Lamessa Melese& Toleha, Hussien Nurahmed. Self-Reported Adverse Drug Reactions, Medication Adherence, and Clinical Outcomes among Major Depressive Disorder Patients in Ethiopia: A Prospective Hospital Based Study. Psychiatry Journal. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1197598
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1197598
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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