Repeated Working Memory Training Improves Task Performance and Neural Efficiency in Multiple Sclerosis Patients and Healthy Controls
المؤلفون المشاركون
Ávila, César
Aguirre, Naiara
Cruz-Gómez, Álvaro Javier
Miró-Padilla, Anna
Bueichekú, Elisenda
Broseta Torres, Ricardo
Sanchis-Segura, Carla
Forn, Cristina
المصدر
Multiple Sclerosis International
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-16
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Background/Objective.
To explore the effectiveness of a specific working memory (WM) training program in MS patients and healthy controls (HC).
Method.
29 MS patients and 29 matched HC were enrolled in the study.
MS and HC were randomly split into two groups: nontraining groups (15HC/14 MS) and training groups (14 HC/15 MS).
Training groups underwent adaptive n-back training (60 min/day; 4 days).
Functional magnetic resonance imaging (fMRI) was used to monitor brain activity during n-back performance (conditions: 0-back, 2-back, and 3-back) at 3 time points: (1) baseline, (2) post-training (+7days), and (3) follow-up (+35days).
Results.
In post-training and follow-up fMRI sessions, trained groups (HC and MS patients) exhibited significant reaction time (RT) reductions and increases in Correct Responses (CRs) during 2-back and 3-back performance.
This improvement of task performance was accompanied by a decrease in brain activation in the WM frontoparietal network.
The two effects were significantly correlated.
Conclusions.
After WM training, both cognitively preserved MS patients and HC participants showed task performance improvement made possible by neuroplastic processes that enhanced neural efficiency.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aguirre, Naiara& Cruz-Gómez, Álvaro Javier& Miró-Padilla, Anna& Bueichekú, Elisenda& Broseta Torres, Ricardo& Ávila, César…[et al.]. 2019. Repeated Working Memory Training Improves Task Performance and Neural Efficiency in Multiple Sclerosis Patients and Healthy Controls. Multiple Sclerosis International،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1200917
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aguirre, Naiara…[et al.]. Repeated Working Memory Training Improves Task Performance and Neural Efficiency in Multiple Sclerosis Patients and Healthy Controls. Multiple Sclerosis International No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1200917
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aguirre, Naiara& Cruz-Gómez, Álvaro Javier& Miró-Padilla, Anna& Bueichekú, Elisenda& Broseta Torres, Ricardo& Ávila, César…[et al.]. Repeated Working Memory Training Improves Task Performance and Neural Efficiency in Multiple Sclerosis Patients and Healthy Controls. Multiple Sclerosis International. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1200917
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1200917
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر