Mesenchymal Stem Cells for the Treatment of Spinal Arthrodesis: From Preclinical Research to Clinical Scenario
المؤلفون المشاركون
Salamanna, Francesca
Sartori, Maria
Fini, Milena
Brodano, G. Barbanti
Griffoni, C.
Martini, L.
Boriani, S.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-27، 27ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-13
دولة النشر
مصر
عدد الصفحات
27
الملخص EN
The use of spinal fusion procedures has rapidly augmented over the last decades and although autogenous bone graft is the “gold standard” for these procedures, alternatives to its use have been investigated over many years.
A number of emerging strategies as well as tissue engineering with mesenchymal stem cells (MSCs) have been planned to enhance spinal fusion rate.
This descriptive systematic literature review summarizes the in vivo studies, dealing with the use of MSCs in spinal arthrodesis surgery and the state of the art in clinical applications.
The review has yielded promising evidence supporting the use of MSCs as a cell-based therapy in spinal fusion procedures, thus representing a suitable biological approach able to reduce the high cost of osteoinductive factors as well as the high dose needed to induce bone formation.
Nevertheless, despite the fact that MSCs therapy is an interesting and important opportunity of research, in this review it was detected that there are still doubts about the optimal cell concentration and delivery method as well as the ideal implantation techniques and the type of scaffolds for cell delivery.
Thus, further inquiry is necessary to carefully evaluate the clinical safety and efficacy of MSCs use in spine fusion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salamanna, Francesca& Sartori, Maria& Brodano, G. Barbanti& Griffoni, C.& Martini, L.& Boriani, S.…[et al.]. 2017. Mesenchymal Stem Cells for the Treatment of Spinal Arthrodesis: From Preclinical Research to Clinical Scenario. Stem Cells International،Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1201189
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salamanna, Francesca…[et al.]. Mesenchymal Stem Cells for the Treatment of Spinal Arthrodesis: From Preclinical Research to Clinical Scenario. Stem Cells International No. 2017 (2017), pp.1-27.
https://search.emarefa.net/detail/BIM-1201189
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salamanna, Francesca& Sartori, Maria& Brodano, G. Barbanti& Griffoni, C.& Martini, L.& Boriani, S.…[et al.]. Mesenchymal Stem Cells for the Treatment of Spinal Arthrodesis: From Preclinical Research to Clinical Scenario. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1201189
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1201189
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر