Visual and Auditory fMRI Paradigms for Presurgical Language Mapping: Convergent Validity and Relationship to Individual Variables
المؤلفون المشاركون
Schmidt, Matthias H.
Omisade, Antonina
O’Grady, Christopher B.
Fisk, John D.
المصدر
Neurology Research International
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-01
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Functional MRI (fMRI) has emerged as a safe alternative to invasive procedures for determining hemispheric language dominance prior to neurosurgery.
Despite this, there are currently no standardized fMRI protocols that have been explored in healthy controls to determine the influence of individual patient variables on the results, which poses challenges in clinical interpretation of ambiguous findings in patient populations.
In addition, most fMRI protocols are not suitable for individuals with visual or intellectual disabilities (IQ<70).
In the current study, 61 healthy adults (ages: 18-74 years) completed two fMRI paradigms for language mapping.
One paradigm used visually based stimuli and has shown good face validity to date in our center.
The second paradigm used auditory stimuli presented at slowed speed and was designed for individuals with visual or cognitive dysfunction but has not yet been used clinically.
The paradigms demonstrated 97% agreement in classifying individuals as left-hemisphere, right-hemisphere, and bilaterally dominant.
Cases that were classified differently showed bilateral dominance in response to either paradigm.
Dominance classification rates for right- and left-handed individuals were largely in keeping with published data.
Within the left-handed group, IQ and education were positively correlated with laterality indices generated by both paradigms (r values range: 0.44-0.95, p<0.01), suggesting that individuals with higher IQ and formal education were more likely to be classified as left-hemisphere dominant in the current sample.
This study will help improve clinical interpretation of language fMRI maps by identifying factors that might impact results (like IQ).
It also offers an alternative paradigm to make this procedure more accessible to a broader range of patients.
Future studies will replicate results with a sample of patients with epilepsy across a broad range of intellectual abilities.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Omisade, Antonina& O’Grady, Christopher B.& Schmidt, Matthias H.& Fisk, John D.. 2019. Visual and Auditory fMRI Paradigms for Presurgical Language Mapping: Convergent Validity and Relationship to Individual Variables. Neurology Research International،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1201747
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Omisade, Antonina…[et al.]. Visual and Auditory fMRI Paradigms for Presurgical Language Mapping: Convergent Validity and Relationship to Individual Variables. Neurology Research International No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1201747
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Omisade, Antonina& O’Grady, Christopher B.& Schmidt, Matthias H.& Fisk, John D.. Visual and Auditory fMRI Paradigms for Presurgical Language Mapping: Convergent Validity and Relationship to Individual Variables. Neurology Research International. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1201747
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1201747
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر