Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect
المؤلفون المشاركون
Scarano, A.
Crincoli, Vito
Mori, Giorgio
Di Benedetto, Adriana
Lorusso, Felice
Cozzolino, Valerio
Kalemaj, Zamira
Grassi, Felice Roberto
Grano, Maria
Podaliri Vulpiani, Michele
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-02
دولة النشر
مصر
عدد الصفحات
9
الملخص EN
Introduction.
Adding stem cells to biodegradable scaffolds to enhance bone regeneration is a valuable option.
Different kinds of stem cells with osteoblastic activity were tested, such as bone marrow stromal stem cells (BMSSCs).
Aim.
To assess a correct protocol for osteogenic stem cell differentiation, so BMSSCs were seeded on a bone porcine block (BPB).
Materials and Methods.
Bone marrow from six minipigs was extracted from tibiae and humeri and treated to isolate BMSSCs.
After seeding on BPB, critical-size defects were created on each mandible of the minipigs and implanted with BPB and BPB/BMSSCs.
After three months, histomorphometric analysis was performed.
Results.
Histomorphometric analysis provided percentages of the three groups.
Tissues present in control defects were 23 ± 2% lamellar bone, 28 ± 1% woven bone, and 56 ± 4% marrow spaces; in BPB defects were 20 ± 5% BPB, 32 ± 2% lamellar bone, 24 ± 1% woven bone, and 28 ± 2% marrow spaces; in BPB/BMSSCs defects were 17 ± 4% BPB/BMSSCs, 42 ± 2% lamellar bone, 12 ± 1% woven bone, and 22 ± 3% marrow spaces.
Conclusion.
BPB used as a scaffold to induce bone regeneration may benefit from the addition of BDPSCs in the tissue-engineered constructs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Scarano, A.& Crincoli, Vito& Di Benedetto, Adriana& Cozzolino, Valerio& Lorusso, Felice& Podaliri Vulpiani, Michele…[et al.]. 2017. Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect. Stem Cells International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1202327
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Scarano, A.…[et al.]. Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect. Stem Cells International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1202327
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Scarano, A.& Crincoli, Vito& Di Benedetto, Adriana& Cozzolino, Valerio& Lorusso, Felice& Podaliri Vulpiani, Michele…[et al.]. Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1202327
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202327
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر