Myocardial Protection from Ischemia-Reperfusion Damage by the Antioxidant Effect of Hibiscus sabdariffa Linnaeus on Metabolic Syndrome Rats
المؤلفون المشاركون
Guarner Lans, Verónica
Díaz-Díaz, Eulises
Pérez-Torres, Israel
Torres-Narváez, Juan Carlos
Perezpeña-Diazconti, Mario
Palacios, Andrea Romero
Manzano-Pech, Linaloe
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-26
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Cardiovascular diseases (CVD) constitute one of the most prevalent health problems worldwide, being strongly associated with metabolic syndrome (MS).
Oxidative stress (OS) is present in both CVD and MS.
Infusions of Hibiscus sabdariffa Linnaeus (HSL) have antioxidant properties and could therefore decrease the presence of OS in these diseases.
The aim of this study was to evaluate myocardial protection during ischemia/reperfusion due to the antioxidant effect of HSL infusion (3%) on a MS rat model induced by the administration of 30% sucrose in drinking water.
We determined in control, MS, and MS+HSL rat hearts (n=6 per group) cardiac mechanical performance (CMP), coronary vascular resistance (CVR), and activities of manganese and copper/zinc superoxide dismutases (Mn and Cu/Zn-SOD), peroxidases, glutathione peroxidase (GPx), catalase (CAT), glutathione s-transferase (GST), glutathione reductase (GR), and glutathione (GSH).
We also determined lipoperoxidation (LPO), total antioxidant capacity (TAC), and the nitrate/nitrite ratio (NO3-/NO2-).
The treatment with the HSL infusion restored the CMP (p=0.01) and CVR (p=0.04) and increased the Mn- (p=0.02), Cu/Zn-SOD (p=0.05), peroxidases (p=0.04), GST (p=0.02) activity, GHS (p=0.02), TAC (p=0.04), and NO3-/NO2- (p=0.01) and decreased the LPO (p=0.02) in the heart of MS rats undergoing ischemia/reperfusion.
The results suggest that the treatment with an infusion from HSL calices protects the cardiac function from damage by ischemia and reperfusion through the antioxidant activities of the substances it possesses.
It favors antioxidant enzymatic activities and nonenzymatic antioxidant capacity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pérez-Torres, Israel& Torres-Narváez, Juan Carlos& Guarner Lans, Verónica& Díaz-Díaz, Eulises& Perezpeña-Diazconti, Mario& Palacios, Andrea Romero…[et al.]. 2019. Myocardial Protection from Ischemia-Reperfusion Damage by the Antioxidant Effect of Hibiscus sabdariffa Linnaeus on Metabolic Syndrome Rats. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1202338
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pérez-Torres, Israel…[et al.]. Myocardial Protection from Ischemia-Reperfusion Damage by the Antioxidant Effect of Hibiscus sabdariffa Linnaeus on Metabolic Syndrome Rats. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1202338
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pérez-Torres, Israel& Torres-Narváez, Juan Carlos& Guarner Lans, Verónica& Díaz-Díaz, Eulises& Perezpeña-Diazconti, Mario& Palacios, Andrea Romero…[et al.]. Myocardial Protection from Ischemia-Reperfusion Damage by the Antioxidant Effect of Hibiscus sabdariffa Linnaeus on Metabolic Syndrome Rats. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1202338
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202338
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر