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Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model
المؤلفون المشاركون
Barnich, Nicolas
Groussard, Carole
Maillard, Florie
Vazeille, Emilie
Sirvent, Pascal
Otero, Yolanda F.
Combaret, Lydie
Madeuf, Elise
Sourdrille, Antoine
Delcros, Geoffroy
Etienne, Monique
Teixeira, Allison
Sauvanet, Pierre
Pialoux, Vincent
Boisseau, Nathalie
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-14
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background and Aim.
Exercise is an effective strategy to reduce obesity-induced oxidative stress.
The purpose of this study was to compare the effects of two training modalities (moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT)) on the pro/antioxidant status of different tissues in obese Zucker rats.
Methods.
Eight-week-old male Zucker rats (fa/fa, n=36) were subdivided in three groups: MICT, HIIT, and control (no exercise) groups.
Trained animals ran on a treadmill (0° slope), 5 days/week for 10 weeks (MICT: 51 min at 12 m·min-1; HIIT: 6 sets of 3 min at 10 m·min-1 followed by 4 min at 18 m·min-1).
Epididymal (visceral) and subcutaneous adipose tissue, gastrocnemius muscle, and plasma samples were collected to measure oxidative stress markers (advanced oxidation protein products (AOPP), oxidized low-density lipoprotein (oxLDL)), antioxidant system markers (ferric-reducing ability of plasma (FRAP), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) activities), and prooxidant enzymes (NADPH oxidase and xanthine oxidase (XO) activities, myeloperoxidase content).
Results.
Compared with the control, MICT increased GPx and catalase activities and the FRAP level in epididymal adipose tissue.
HIIT increased the AOPP level in subcutaneous adipose tissue.
In the muscle, HIIT increased both SOD and GPx activities and reduced the AOPP level, whereas MICT increased only SOD activity.
Finally, plasma myeloperoxidase content was similarly decreased by both training modalities, whereas oxLDL was reduced only in the MICT group.
Conclusion.
Both HIIT and MICT improved the pro/antioxidant status.
However, HIIT was more efficient than MICT in the skeletal muscle, whereas MICT was more efficient in epididymal adipose tissue.
This suggests that oxidative stress responses to HIIT and MICT are tissue-specific.
This could result in ROS generation via different pathways in these tissues.
From a practical point of view, the two training modalities should be combined to obtain a global response in people with obesity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Groussard, Carole& Maillard, Florie& Vazeille, Emilie& Barnich, Nicolas& Sirvent, Pascal& Otero, Yolanda F.…[et al.]. 2019. Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1202442
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Groussard, Carole…[et al.]. Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1202442
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Groussard, Carole& Maillard, Florie& Vazeille, Emilie& Barnich, Nicolas& Sirvent, Pascal& Otero, Yolanda F.…[et al.]. Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1202442
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202442
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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