Abnormal Regional Spontaneous Neural Activity in Nonarteritic Anterior Ischemic Optic Neuropathy: A Resting-State Functional MRI Study
المؤلفون المشاركون
Su, Yan
Zhao, Pengbo
Guo, Pengde
Lv, Han
Chen, Yunxiang
Hua, Haiqin
Kang, Shaohong
Wang, Yan
Liu, Ming
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To explore altered regional neuronal activity in patients with nonarteritic anterior ischemic optic neuropathy (NAION) and its correlation with clinical performances using the regional homogeneity (ReHo) method, which is based on resting-state functional magnetic resonance imaging (fMRI).
Method.
Thirty-one patients with NAION (20 males, 11 females) and 31 age- and sex-matched normal controls (NCs) (20 males, 11 females) were enrolled in the study.
All patients underwent ophthalmic examination, including eyesight, intraocular pressure measurement, optimal coherence tomography (OCT), visual field analysis, and fMRI scans.
After ReHo was calculated, we investigated group differences in results between the patients and NCs.
We analyzed the relationship between ReHo values for different brain regions in patients with NAION and intraocular pressure, visual field analysis, and OCT.
A receiver operating characteristic (ROC) curve was used to assess the diagnostic ability of the ReHo method.
Results.
Compared with NCs, patients with NAION exhibited higher ReHo values in the left middle frontal gyrus, left middle cingulate gyrus, left superior temporal gyrus, and left inferior parietal lobule.
Additionally, they exhibited lower ReHo values in the right lingual gyrus, left putamen/lentiform nucleus, and left superior parietal lobule.
ReHo values in the left superior parietal lobule were negatively correlated with right retinal nerve fiber layer values (r=−0.462, P=0.01).
The area under the ROC curve for each brain region indicated that the ReHo method is a credible means of diagnosing patient with NAION.
Conclusion.
NAION was primarily associated with dysfunction in the default mode network, which may reflect its underlying neural mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guo, Pengde& Zhao, Pengbo& Lv, Han& Su, Yan& Liu, Ming& Chen, Yunxiang…[et al.]. 2020. Abnormal Regional Spontaneous Neural Activity in Nonarteritic Anterior Ischemic Optic Neuropathy: A Resting-State Functional MRI Study. Neural Plasticity،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1202844
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guo, Pengde…[et al.]. Abnormal Regional Spontaneous Neural Activity in Nonarteritic Anterior Ischemic Optic Neuropathy: A Resting-State Functional MRI Study. Neural Plasticity No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1202844
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guo, Pengde& Zhao, Pengbo& Lv, Han& Su, Yan& Liu, Ming& Chen, Yunxiang…[et al.]. Abnormal Regional Spontaneous Neural Activity in Nonarteritic Anterior Ischemic Optic Neuropathy: A Resting-State Functional MRI Study. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1202844
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202844
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر