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The Effects of GABAergic System under Cerebral Ischemia: Spotlight on Cognitive Function
المؤلفون المشاركون
Li, Juan
Guo, Feng
Chen, Luting
Han, Xiaohua
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
In this review, we present evidence about the changes of the GABAergic system on the hippocampus under the ischemic environment, which may be an underlying mechanism to the ischemia-induced cognitive deficit.
GABAergic system, in contrast to the glutamatergic system, is considered to play an inhibitory effect on the central nervous system over the past several decades.
It has received widespread attention in the area of schizophrenia and epilepsy.
The GABAergic system has a significant effect in promoting neural development and formation of local neural circuits of the brain, which is the structural basis of cognitive function.
There have been a number of reviews describing changes in the GABAergic system in cerebral ischemia in recent years.
However, no study has investigated the changes in the system in the hippocampus during cerebral ischemic injury, which results in cognitive impairment, particularly at the chronic ischemic stage and the late phase of ischemia.
We present a review of the changes of the GABAergic system in the hippocampus under ischemia, including GABA interneurons, extracellular GABA neurotransmitter, and GABA receptors.
Several studies are also listed correlating amelioration of cognitive impairment by regulating the GABAergic system in the hippocampus damaged under ischemia.
Furthermore, exogenous cell transplantation, which improves cognition by modulating the GABAergic system, will also be described in this review to bring new insight and strategy on solving cognitive deficits caused by cerebral ischemia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Juan& Chen, Luting& Guo, Feng& Han, Xiaohua. 2020. The Effects of GABAergic System under Cerebral Ischemia: Spotlight on Cognitive Function. Neural Plasticity،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1202961
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Juan…[et al.]. The Effects of GABAergic System under Cerebral Ischemia: Spotlight on Cognitive Function. Neural Plasticity No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1202961
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Juan& Chen, Luting& Guo, Feng& Han, Xiaohua. The Effects of GABAergic System under Cerebral Ischemia: Spotlight on Cognitive Function. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1202961
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202961
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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