Antioxidant Effect of a Polyphenol-Rich Murtilla (Ugni molinae Turcz.) Extract and Its Effect on the Regulation of Metabolism in Refrigerated Boar Sperm
المؤلفون المشاركون
Alvear, Marysol
Nichi, Marcílio
Assumpção, Mayra Elena Ortiz D’Ávila
Jofré, Ignacio
Cuevas, Magdalena
Scheuermann, Erick
Romero, Fernando
de Castro, Letícia S.
Losano, João D. A.
Torres, Mariana Andrade
Andrade, André Furugen Cesar
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-03
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
The production of reactive oxygen species (ROS) in boar spermatozoa increases in refrigeration; this can have an impact on sperm quality and fertilization capacity.
We evaluated the effect of polyphenol-rich aqueous extract of murtilla (Ugni molinae Turcz) on boar sperm stored at 17°C in order to reduce oxidative stress and improve sperm quality in the long term.
Five experiments were performed: first, characterization of the polyphenol content from five genotypes of murtilla; second, determination of the genotype with the best antioxidant effect (MT-Ex); third, the antioxidant capacity on O2- and lipid peroxidation; fourth, the influence of MT-Ex on motility, calcium movement, cAMP, and metabolic parameters; and fifth, analysis of long-term refrigeration.
The average phenolic content was 344 ppm; gallic acid, catechin, quercetin, myricetin, and kaempferol were detected.
All extracts evaluated presented a concentration-dependent antioxidant effect.
MT-Ex reduces intracellular O2-/peroxides but low lipid peroxidation.
MT-Ex in nonstimulated ROS conditions reduces sperm motility, mitochondrial membrane potential, cAMP, and ATP, but the succinate dehydrogenase activity remained normal; also, we observed a reduction in calcium movement in in vitro sperm capacitation.
The long-term analyses showed that MT-Ex improved sperm motility decay and reduced membrane damage and ROS at 168 h.
Based on this study, we propose MT-Ex as a supplement in semen extenders.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jofré, Ignacio& Cuevas, Magdalena& de Castro, Letícia S.& Losano, João D. A.& Torres, Mariana Andrade& Alvear, Marysol…[et al.]. 2019. Antioxidant Effect of a Polyphenol-Rich Murtilla (Ugni molinae Turcz.) Extract and Its Effect on the Regulation of Metabolism in Refrigerated Boar Sperm. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1202990
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jofré, Ignacio…[et al.]. Antioxidant Effect of a Polyphenol-Rich Murtilla (Ugni molinae Turcz.) Extract and Its Effect on the Regulation of Metabolism in Refrigerated Boar Sperm. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-15.
https://search.emarefa.net/detail/BIM-1202990
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jofré, Ignacio& Cuevas, Magdalena& de Castro, Letícia S.& Losano, João D. A.& Torres, Mariana Andrade& Alvear, Marysol…[et al.]. Antioxidant Effect of a Polyphenol-Rich Murtilla (Ugni molinae Turcz.) Extract and Its Effect on the Regulation of Metabolism in Refrigerated Boar Sperm. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-15.
https://search.emarefa.net/detail/BIM-1202990
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1202990
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر