Symptomatic Primary Hyperparathyroidism as a Risk Factor for Differentiated Thyroid Cancer
المؤلفون المشاركون
Ramírez-Rentería, Claudia
Vargas, Guadalupe
Gonzalez, Baldomero
Mendoza, Victoria
Mercado, Moisés
Balcázar-Hernández, Lourdes Josefina
Nieto-Guzmán, Oriana
Garrido-Mendoza, Ana Pamela
Flores-Maya, Marco Antonio
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The primary hyperparathyroidism (PHPT) is a common disease for the endocrinologist.
The concomitant thyroid disease and differentiated thyroid cancer (DTC) appear to be more frequent in patients with PHPT than in the general population.
The aim of this study was to characterize patients with symptomatic PHPT with and without DTC and analyze frequency and risk factors.
Methods.
We consecutively studied patients with symptomatic PHPT diagnosed and treated at our center between 2013 and 2015.
Patients with subclinical and syndromic forms of PHPT were excluded.
Clinical and biochemical characteristics of patients with and without DTC were compared and risk factors were determined.
All patients were studied with thyroid ultrasound and thyroid gammagraphy with TC-MIBI.
Two expert surgeons performed all the surgical procedures.
Results.
In 59 patients included, we found 12 cases of PTC (20.3%).
The final histopathological report of the PTC was 7 cases of follicular variant, 2 cases of oncocytic variant, 2 cases of classic variant, and 1 case of columnar cells variant of PTC.
Patients with thyroid cancer were older than patients without thyroid cancer (62 ± 9.5 versus 52 ± 15.8, p = 0.03).
Higher preoperative levels of iPTH were associated with PTC (p=0.03) [OR 5.16 (95% CI: 1.08-24.7)].
Conclusion.
PTC is frequent in patients with symptomatic PHPT.
Thyroid nodules in patients with symptomatic PHPT must be studied before parathyroidectomy.
In symptomatic PHPT, higher level concentration of parathormone (PTH) was associated with higher risk of DTC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vargas, Guadalupe& Balcázar-Hernández, Lourdes Josefina& Gonzalez, Baldomero& Ramírez-Rentería, Claudia& Nieto-Guzmán, Oriana& Garrido-Mendoza, Ana Pamela…[et al.]. 2018. Symptomatic Primary Hyperparathyroidism as a Risk Factor for Differentiated Thyroid Cancer. Journal of Thyroid Research،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1203107
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vargas, Guadalupe…[et al.]. Symptomatic Primary Hyperparathyroidism as a Risk Factor for Differentiated Thyroid Cancer. Journal of Thyroid Research No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1203107
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vargas, Guadalupe& Balcázar-Hernández, Lourdes Josefina& Gonzalez, Baldomero& Ramírez-Rentería, Claudia& Nieto-Guzmán, Oriana& Garrido-Mendoza, Ana Pamela…[et al.]. Symptomatic Primary Hyperparathyroidism as a Risk Factor for Differentiated Thyroid Cancer. Journal of Thyroid Research. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1203107
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203107
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر