Renal Dysfunction after Living-Donor Liver Transplantation: Experience with 500 Cases
المؤلفون المشاركون
Abdel-Khalek, Ehab E.
Alrefaey, Alrefaey K.
Yassen, Amr M.
Monier, Ahmed
Elgouhari, Hesham M.
Habl, Mohamed Samy
Tawfik, Gehad
Elzayat, Thuraya
Zayed, Reham Adly
Abdel-Wahab, Mohamed
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-23
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
The possible risk factors for chronic kidney disease in transplant recipients have not been thoroughly investigated after living-donor liver transplantation.
Material and Methods.
A retrospective cohort study of consecutive adults who underwent living-donor liver transplantation between May 2004 and October 2016, in a single center, was conducted.
Kidney function was investigated successively for all the patients throughout the study period, with 12 months being the shortest follow-up.
Postoperative renal dysfunction was defined in accordance with the Chronic Kidney Disease Epidemiology Collaboration criteria.
The patients’ demographic data, preoperative and intraoperative parameters, and outcomes were recorded.
A calcineurin inhibitor-based immunosuppressive regimen, either tacrolimus or cyclosporine, was used in all the patients.
Results.
Of the 413 patients included in the study, 33 (8%) who survived for ≥1 year experienced chronic kidney disease 1 year after living-donor liver transplantation.
Twenty-seven variables were studied to compare between the patients with normal kidney functions and those who developed chronic kidney disease 1 year after living-donor liver transplantation.
Univariate regression analysis for predicting the likelihood of chronic kidney disease at 1 year revealed that the following 4 variables were significant: operative time, P < 0.0005; intraoperative blood loss, P < 0.0005; preoperative renal impairment, P = 0.001; and graft-to-recipient weight ratio (as a negative predictor), P < 0.0005.
In the multivariate regression analysis, only 2 variables remained as independent predictors of chronic kidney disease at 1 year, namely, operative time with a cutoff value of ≥714 minutes and graft-to-recipient weight ratio as a negative predictor with a cutoff value of <0.91.
Conclusion.
In this study, prolonged operative time and small graft-to-recipient weight ratio were independent predictors of chronic kidney disease at 1 year after living-donor liver transplantation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdel-Khalek, Ehab E.& Alrefaey, Alrefaey K.& Yassen, Amr M.& Monier, Ahmed& Elgouhari, Hesham M.& Habl, Mohamed Samy…[et al.]. 2018. Renal Dysfunction after Living-Donor Liver Transplantation: Experience with 500 Cases. Journal of Transplantation،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1203142
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdel-Khalek, Ehab E.…[et al.]. Renal Dysfunction after Living-Donor Liver Transplantation: Experience with 500 Cases. Journal of Transplantation No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1203142
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdel-Khalek, Ehab E.& Alrefaey, Alrefaey K.& Yassen, Amr M.& Monier, Ahmed& Elgouhari, Hesham M.& Habl, Mohamed Samy…[et al.]. Renal Dysfunction after Living-Donor Liver Transplantation: Experience with 500 Cases. Journal of Transplantation. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1203142
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203142
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر