Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly
المؤلفون المشاركون
Connes, Philippe
Pialoux, Vincent
Faes, Camille
Raberin, Antoine
Barthélémy, Jean-Claude
Robert, Pia
Celle, Sébastien
Hupin, David
Rytz, Chantal
Roche, Frédéric
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-19
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Cardiovascular diseases remain as the leading cause of morbidity and mortality in industrialized countries.
Ageing and gender strongly modulate the risk to develop cardiovascular diseases but very few studies have investigated the impact of gender on cardiovascular diseases in the elderly, which represents a growing population.
The purpose of this study was to test the impact of gender and physical activity level on several biochemical and clinical markers of cardiovascular risk in elderly individuals.
Methods.
Elderly individuals (318 women (75.8±1.2 years-old) and 227 men (75.8±1.1 years-old)) were recruited.
Physical activity was measured by a questionnaire.
Metabolic syndrome was defined using the National Cholesterol Education Program Expert Panel’s definition.
Polysomnography and digital tonometry were used to detect obstructive sleep apnea and assess vascular reactivity, respectively.
Blood was sampled to measure several oxidative stress markers and adhesion molecules.
Results.
The frequency of cardiovascular diseases was significantly higher in men (16.4%) than in women (6.1%) (p<0.001).
Body mass index (25.0±4.3 vs.
25.8±3.13 kg.m−2) and glycaemia (94.9±16.5 vs.
101.5±22.6 mg.dL−1) were lower, and High Density Lipoprotein (HDL) (74.6±17.8 vs.
65.0±17.2 mg.dL−1) was higher in women compared to men (p<0.05).
Oxidative stress was lower in women than in men (uric acid: 52.05±13.78 vs.
59.84±13.58, advanced oxidation protein products: 223±94 vs.
246±101 μmol.L−1, malondialdehyde: 22.44±6.81 vs.
23.88±9.74 nmol.L−1).
Physical activity was not associated with lower cardiovascular risk factors in both genders.
Multivariate analyses showed an independent effect of gender on acid uric (β=0.182; p=0.020), advanced oxidation protein products (β=0.257; p<0.001), and HDL concentration (β=−0.182; p=0.026).
Conclusion.
These findings suggest that biochemical cardiovascular risk factors are lower in women than men which could explain the lower cardiovascular disease proportion observed in women in the elderly.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Raberin, Antoine& Connes, Philippe& Barthélémy, Jean-Claude& Robert, Pia& Celle, Sébastien& Hupin, David…[et al.]. 2020. Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1203666
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Raberin, Antoine…[et al.]. Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1203666
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Raberin, Antoine& Connes, Philippe& Barthélémy, Jean-Claude& Robert, Pia& Celle, Sébastien& Hupin, David…[et al.]. Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1203666
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203666
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر