Proteome and Transcriptome Analysis of the Antioxidant Mechanism in Chicken Regulated by Eucalyptus Leaf Polyphenols Extract
المؤلفون المشاركون
Li, Wei
He, Ze-qi
Zhang, Xiao-Ying
Chen, Yun-Jiao
Zuo, Jian-Jun
Cao, Yong
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-15
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Eucalyptus leaf polyphenols extract (EPE) has been proved to have various bioactivities, but few reports focus on its antioxidant mechanism in vivo.
The purpose of this study was to elucidate the effect and mechanism of EPE dietary supplements on antioxidant capacity in chicken.
A total of 216 chickens were randomly selected for a 40-day experiment.
Four treatment groups received diets including the control diet only, the control diet + low EPE (0.6 g/kg), the control diet + moderate EPE (0.9 g/kg), and the control diet + high EPE (1.2 g/kg).
Compared with control group, the glutathione peroxidase (GSH-Px) activity and glutathione (GSH) content in the breast muscle of the moderate EPE treatment group was significantly higher (p<0.05), while the malonaldehyde (MDA) content in the moderate EPE group was reduced (p<0.05).
Moreover, proteomic and transcriptomic analyses of the breast muscle revealed that glutathione metabolism and the peroxisome were the two crucial metabolic pathways responsible for increased antioxidant capacity of the muscle.
Accordingly, nine candidate genes and two candidate proteins were identified related to improved antioxidant status induced by EPE supplements.
This research provides new insights into the molecular mechanism of antioxidant capacity in chickens treated with EPE dietary supplements.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Wei& He, Ze-qi& Zhang, Xiao-Ying& Chen, Yun-Jiao& Zuo, Jian-Jun& Cao, Yong. 2020. Proteome and Transcriptome Analysis of the Antioxidant Mechanism in Chicken Regulated by Eucalyptus Leaf Polyphenols Extract. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1203704
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Wei…[et al.]. Proteome and Transcriptome Analysis of the Antioxidant Mechanism in Chicken Regulated by Eucalyptus Leaf Polyphenols Extract. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1203704
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Wei& He, Ze-qi& Zhang, Xiao-Ying& Chen, Yun-Jiao& Zuo, Jian-Jun& Cao, Yong. Proteome and Transcriptome Analysis of the Antioxidant Mechanism in Chicken Regulated by Eucalyptus Leaf Polyphenols Extract. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1203704
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1203704
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر