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Potential Therapeutic Role of Dietary Supplementation with Spirulina platensis on the Erectile Function of Obese Rats Fed a Hypercaloric Diet
المؤلفون المشاركون
Diniz, Anderson Fellyp Avelino
de Souza, Iara Leão Luna
dos Santos Ferreira, Elba
de Lima Carvalho, Maria Thaynan
Barros, Bárbara Cavalcanti
Ferreira, Paula Benvindo
da Conceição Correia Silva, Maria
Júnior, Francisco Fernandes Lacerda
de Lima Tavares Toscano, Lydiane
Silva, Alexandre Sérgio
de Andrade Cavalcante, Fabiana
da Silva, Bagnólia Araújo
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-30
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Spirulina platensis, an important source of bioactive compounds, is a multicellular, filamentous cyanobacterium rich in high-quality proteins, vitamins, minerals, and antioxidants.
Due to its nutrient composition, the alga is considered a complete food and is recognized for its anti-inflammatory, antioxidant, antiobesity, and reproprotective effects.
All of which are important for prevention and treatment of organic and metabolic disorders such as obesity and erectile dysfunction.
The aim of this study was to investigate the modulatory role of Spirulina platensis food supplementation and the mechanisms of action involved in reversing the damage caused by a hypercaloric diet on the erectile function of rats.
The animals were divided into a standard diet group (SD, n=5); a hypercaloric diet group (HCD, n=5); a hypercaloric diet group supplemented with S.
platensis at doses of 25 (HCD+SP25, n=5), 50 (HCD+SP50, n=5), and 100 mg/kg (HCD+SP100, n=5); and a hypercaloric diet group subsequently fed a standard diet (HCD+SD, n=5).
In the rats fed a hypercaloric diet, dietary supplementation with S.
platensis effectively increased the number of erections while decreasing latency to initiate penile erection.
Additionally, S.
platensis increases NO bioavailability, reduces inflammation by reducing the release of contractile prostanoids, enhances the relaxation effect promoted by acetylcholine (ACh), restores contractile reactivity damage and cavernous relaxation, reduces reactive oxygen species (ROS), and increases cavernous total antioxidant capacity (TAC).
Food supplementation with S.
platensis thus restores erectile function in obese rats, reduces production of contractile prostanoids, reduces oxidative stress, and increases NO bioavailability.
Food supplementation with S.
platensis thus emerges as a promising new therapeutic alternative for the treatment of erectile dysfunction as induced by obesity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Diniz, Anderson Fellyp Avelino& de Souza, Iara Leão Luna& dos Santos Ferreira, Elba& de Lima Carvalho, Maria Thaynan& Barros, Bárbara Cavalcanti& Ferreira, Paula Benvindo…[et al.]. 2020. Potential Therapeutic Role of Dietary Supplementation with Spirulina platensis on the Erectile Function of Obese Rats Fed a Hypercaloric Diet. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1204233
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Diniz, Anderson Fellyp Avelino…[et al.]. Potential Therapeutic Role of Dietary Supplementation with Spirulina platensis on the Erectile Function of Obese Rats Fed a Hypercaloric Diet. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1204233
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Diniz, Anderson Fellyp Avelino& de Souza, Iara Leão Luna& dos Santos Ferreira, Elba& de Lima Carvalho, Maria Thaynan& Barros, Bárbara Cavalcanti& Ferreira, Paula Benvindo…[et al.]. Potential Therapeutic Role of Dietary Supplementation with Spirulina platensis on the Erectile Function of Obese Rats Fed a Hypercaloric Diet. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1204233
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1204233
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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