Single Bout Exercise in Children with Juvenile Idiopathic Arthritis: Impact on Inflammatory Markers

المؤلفون المشاركون

Evrard, Bertrand
Rochette, Emmanuelle
Duché, Pascale
Hourdé, Christophe
Echaubard, Stéphane
Merlin, Etienne
Pereira, Bruno

المصدر

Mediators of Inflammation

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-06-13

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الأمراض

الملخص EN

Objective.

In a context of inflammatory disease such as juvenile idiopathic arthritis (JIA), we do not know what impact physical activity may have on a deregulated immune system.

The objective is to measure the impact of a single bout of exercise on plasma inflammatory markers such as calprotectin, IL-6, sIL-6R, sgp130, and the hypothalamic-pituitary-adrenal axis in children with juvenile idiopathic arthritis.

Methods.

Twelve children with JIA performed a nonexercise control day and a consecutive day that included a 20 min exercise bout at 70% of max-HR at 08:30 am.

Venous blood samples were taken at 08:30, 08:50, 09:30, 10:30 am, and 12:00 pm to measure plasma concentrations of calprotectin, IL-6, sIL-6R, sgp130, cortisol, and ACTH.

Pain was evaluated at 08:30, 08:50 am, and 06:00 pm.

Results.

There was a transient twofold increase in postexercise self-evaluated pain (p=0.03) that disappeared in the evening.

A single bout of exercise resulted in a 1.7-fold increase in plasma calprotectin (p<0.001) but not IL-6 and its soluble receptors.

Calprotectin levels returned to baseline within 3 hours after cessation of exercise.

Conclusion.

Acute exercise in children with JIA induced slightly musculoskeletal leg pain and transient increased plasma calprotectin levels but not IL-6 levels.

Trial registration in ClinicalTrials.gov, reference number NCT 02502539, registered on 29 May 2015.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Rochette, Emmanuelle& Duché, Pascale& Hourdé, Christophe& Evrard, Bertrand& Pereira, Bruno& Echaubard, Stéphane…[et al.]. 2018. Single Bout Exercise in Children with Juvenile Idiopathic Arthritis: Impact on Inflammatory Markers. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1204451

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Rochette, Emmanuelle…[et al.]. Single Bout Exercise in Children with Juvenile Idiopathic Arthritis: Impact on Inflammatory Markers. Mediators of Inflammation No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1204451

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Rochette, Emmanuelle& Duché, Pascale& Hourdé, Christophe& Evrard, Bertrand& Pereira, Bruno& Echaubard, Stéphane…[et al.]. Single Bout Exercise in Children with Juvenile Idiopathic Arthritis: Impact on Inflammatory Markers. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1204451

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1204451