Inhibitory Effect of Lactobacillus plantarum CCFM8724 towards Streptococcus mutans- and Candida albicans-Induced Caries in Rats
المؤلفون المشاركون
Zhang, Qiuxiang
Qin, Sujia
Xu, Xianyin
Zhao, Jianxin
Zhang, Hao
Liu, Zhenmin
Chen, Wei
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-21
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Streptococcus mutans is a recognized cariogenic bacterium and a major producer of biofilm matrix.
The presence of Candida albicans in dental plaque with S.
mutans enhances the virulence leading to the onset of rampant caries which is similar to early childhood caries (ECC).
The purpose of this study was to explore the effect of Lactobacillus plantarum CCFM8724 (CCFM8724) on the treatment and prevention of dental caries induced by S.
mutans and C.
albicans in vivo.
Rats were divided into 6 groups: the control group and model group, 2 treatment groups, and 2 prevention groups (0.02% chlorhexidine or CCFM8724).
The fluctuation of microbial colonization and the change of bacteria flora in rat oral cavity after sowing of L.
plantarum CCFM8724 were investigated by colony-forming units (CFU) and microflora analysis.
The caries of rats were assessed by microcomputed tomography (micro-CT) and Keyes scoring method.
The results showed that L.
plantarum CCFM8724 in both the treatment and prevention groups could significantly decrease the population of S.
mutans and C.
albicans in the rats’ oral cavity (p<0.001), the mineral loss of enamel (p<0.05), and the scores of caries (p<0.05).
Besides, L.
plantarum CCFM8724 exhibited better effects than chlorhexidine.
Hence, L.
plantarum CCFM8724 was proved to be a potential oral probiotic on caries treatment and prevention in vivo and it may have the prospect of application in dental caries (especially ECC) prevention products.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Qiuxiang& Qin, Sujia& Xu, Xianyin& Zhao, Jianxin& Zhang, Hao& Liu, Zhenmin…[et al.]. 2020. Inhibitory Effect of Lactobacillus plantarum CCFM8724 towards Streptococcus mutans- and Candida albicans-Induced Caries in Rats. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1204517
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Qiuxiang…[et al.]. Inhibitory Effect of Lactobacillus plantarum CCFM8724 towards Streptococcus mutans- and Candida albicans-Induced Caries in Rats. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1204517
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Qiuxiang& Qin, Sujia& Xu, Xianyin& Zhao, Jianxin& Zhang, Hao& Liu, Zhenmin…[et al.]. Inhibitory Effect of Lactobacillus plantarum CCFM8724 towards Streptococcus mutans- and Candida albicans-Induced Caries in Rats. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1204517
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1204517
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر