Effect of Hypovitaminosis D on Lipid Profile in Hypothyroid Patients in Saudi Arabia
المؤلفون المشاركون
Alsamghan, Awad S.
Alsaleem, Safar A.
Alzahrani, Mohammed A. S.
Patel, Ayyub
Mallick, Ayaz K.
Sheweita, Salah A.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-24
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Hypothyroidism is believed to be associated with dyslipidemia and is considered a risk factor for the development of atherosclerotic cardiovascular diseases (ASCVD).
Vitamin D, due to its steroid hormone action, retains cell function and controls the metabolism of lipids.
Therefore, the present study was carried out to show the association of the risk factors of ASCVD and deficiency of thyroid hormones and vitamin D levels since no previous studies have been performed on Saudi patients before.
Methodology.
A retrospective cohort study was carried out on 400 hypothyroid patients.
Medical records of those patients were followed up and were classified as normal and hypothyroid patients according to their thyroid-stimulating hormone levels.
TSH, vitamin D, and lipid profiles were determined using the ELISA technique.
Result.
Total cholesterol, triglyceride, and low-density lipoprotein cholesterol levels were significantly higher in hypothyroid patients than those in the normal group.
We have found a significant correlation between TSH levels and the risk factors of ASCVD (total cholesterol, triglycerides, and LDL-C).
Moreover, a significant correlation between vitamin D levels and the risk factors of ASCVD (total cholesterol, triglycerides, and LDL-C) has been found.
In addition, there is a correlation between deficiency of Vit D and low-TSH levels (95% CI 1.092–4.05) indicating a higher risk for the development of ASCVD among those patients.
Conclusion.
Hypothyroid and vitamin D-deficient patients must be screened regularly at an early stage to predict and also to prevent cardiovascular diseases.
Moreover, an adequate supply of vitamin D and TH should be given to those patients to prevent cardiovascular diseases at an early stage.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alsamghan, Awad S.& Alsaleem, Safar A.& Alzahrani, Mohammed A. S.& Patel, Ayyub& Mallick, Ayaz K.& Sheweita, Salah A.. 2020. Effect of Hypovitaminosis D on Lipid Profile in Hypothyroid Patients in Saudi Arabia. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1205181
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alsamghan, Awad S.…[et al.]. Effect of Hypovitaminosis D on Lipid Profile in Hypothyroid Patients in Saudi Arabia. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1205181
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alsamghan, Awad S.& Alsaleem, Safar A.& Alzahrani, Mohammed A. S.& Patel, Ayyub& Mallick, Ayaz K.& Sheweita, Salah A.. Effect of Hypovitaminosis D on Lipid Profile in Hypothyroid Patients in Saudi Arabia. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1205181
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1205181
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر