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Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing
المؤلفون المشاركون
Ma, Zhiqiang
Xu, Liqun
Liu, Dong
Zhang, Xiaoyan
Di, Shouyin
Li, Weimiao
Zhang, Jiao
Han, Jing
Li, Xiaofei
Yan, Xiaolong
Reiter, Russel J.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-20، 20ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-21
دولة النشر
مصر
عدد الصفحات
20
التخصصات الرئيسية
الملخص EN
Persistent senescence seems to exert detrimental effects fostering ageing and age-related disorders, such as cancer.
Chemotherapy is one of the most valuable treatments for cancer, but its clinical application is limited due to adverse side effects.
Melatonin is a potent antioxidant and antiageing molecule, is nontoxic, and enhances the efficacy and reduces the side effects of chemotherapy.
In this review, we first summarize the mitochondrial protective role of melatonin in the context of chemotherapeutic drug-induced toxicity.
Thereafter, we tabulate the protective actions of melatonin against ageing and the harmful roles induced by chemotherapy and chemotherapeutic agents, including anthracyclines, alkylating agents, platinum, antimetabolites, mitotic inhibitors, and molecular-targeted agents.
Finally, we discuss several novel directions for future research in this area.
The information compiled in this review will provide a comprehensive reference for the protective activities of melatonin in the context of chemotherapy drug-induced toxicity and will contribute to the design of future studies and increase the potential of melatonin as a therapeutic agent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ma, Zhiqiang& Xu, Liqun& Liu, Dong& Zhang, Xiaoyan& Di, Shouyin& Li, Weimiao…[et al.]. 2020. Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-20.
https://search.emarefa.net/detail/BIM-1205225
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ma, Zhiqiang…[et al.]. Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-20.
https://search.emarefa.net/detail/BIM-1205225
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ma, Zhiqiang& Xu, Liqun& Liu, Dong& Zhang, Xiaoyan& Di, Shouyin& Li, Weimiao…[et al.]. Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-20.
https://search.emarefa.net/detail/BIM-1205225
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1205225
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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