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QT and QTc in Male Patients with Psychotic Disorders Treated with Atypical Neuroleptics
المؤلفون المشاركون
Simoncini, Marly
Miniati, Mario
Carmassi, Claudia
Massimetti, Gabriele
Vanelli, Federica
Franceschini, Caterina
Dell'Osso, Liliana
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-12
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Objective.
We explored the potential association between antipsychotics and QT/QTc duration changes in hospitalized male patients with psychotic disorders.
Methods.
The chart review was conducted on 184 male patients hospitalized between 2013 and 2015 at the Psychiatric Clinic of Pisa, Italy.
Patients who were treated with one atypical antipsychotic at the time of the ECG recording were 109/184 (59.2%).
QT/QTc were compared considering the atypical antipsychotic received.
Results.
96.3% (n = 105/109) of the sample showed QTc values ≤ 430 ms; 4 patients (3.7%) had QTc values between 430 and 450 msec (2 with paliperidone, 1 with risperidone, and 1 with olanzapine).
The mean QT duration of the overall sample was 368.0 ± 28.0 and the mean QTc 400.1 ± 17.8.
QTc values did not reveal statistically significant differences.
QT values were significantly different (chi-square = 17.3; df = 5; p = .004).
Statistically significant differences between aripiprazole and paliperidone (349.0 ± 28.3 versus 390.5 ± 29.8; p = .002) and between clozapine and paliperidone (361.1 ± 22.43 versus 390.5 ± 29.8; p = .033) were found.
Conclusions.
Aripiprazole was the least interfering neuroleptic with QT/QTc.
Paliperidone was the atypical neuroleptic with the most relevant difference with aripiprazole, but only on QT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Miniati, Mario& Simoncini, Marly& Vanelli, Federica& Franceschini, Caterina& Massimetti, Gabriele& Carmassi, Claudia…[et al.]. 2017. QT and QTc in Male Patients with Psychotic Disorders Treated with Atypical Neuroleptics. The Scientific World Journal،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1205314
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Miniati, Mario…[et al.]. QT and QTc in Male Patients with Psychotic Disorders Treated with Atypical Neuroleptics. The Scientific World Journal No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1205314
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Miniati, Mario& Simoncini, Marly& Vanelli, Federica& Franceschini, Caterina& Massimetti, Gabriele& Carmassi, Claudia…[et al.]. QT and QTc in Male Patients with Psychotic Disorders Treated with Atypical Neuroleptics. The Scientific World Journal. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1205314
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1205314
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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