A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols
المؤلفون المشاركون
Jeffree, Mohammad Saffree
Pasupuleti, Visweswara Rao
Arigela, Chandra Sekhar
Gan, Siew Hua
Salam, Sirajudeen Kuttulebbai Nainamohamed
Krishnan, Kumara Thevan
Rahman, Nurhanan Abdul
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-23
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Despite the availability of various antidiabetic drugs, diabetes mellitus (DM) remains one of the world’s most prevalent chronic diseases and is a global burden.
Hyperglycaemia, a characteristic of type 2 diabetes mellitus (T2DM), substantially leads to the generation of reactive oxygen species (ROS), triggering oxidative stress as well as numerous cellular and molecular modifications such as mitochondrial dysfunction affecting normal physiological functions in the body.
In mitochondrial-mediated processes, oxidative pathways play an important role, although the responsible molecular mechanisms remain unclear.
The impaired mitochondrial function is evidenced by insulin insensitivity in various cell types.
In addition, the roles of master antioxidant pathway nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)/antioxidant response elements (ARE) are being deciphered to explain various molecular pathways involved in diabetes.
Dietary factors are known to influence diabetes, and many natural dietary factors have been studied to improve diabetes.
Honey is primarily rich in carbohydrates and is also abundant in flavonoids and phenolic acids; thus, it is a promising therapeutic antioxidant for various disorders.
Various research has indicated that honey has strong wound-healing properties and has antibacterial, anti-inflammatory, antifungal, and antiviral effects; thus, it is a promising antidiabetic agent.
The potential antidiabetic mechanisms of honey were proposed based on its major constituents.
This review focuses on the various prospects of using honey as an antidiabetic agent and the potential insights.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pasupuleti, Visweswara Rao& Arigela, Chandra Sekhar& Gan, Siew Hua& Salam, Sirajudeen Kuttulebbai Nainamohamed& Krishnan, Kumara Thevan& Rahman, Nurhanan Abdul…[et al.]. 2020. A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-16.
https://search.emarefa.net/detail/BIM-1205853
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pasupuleti, Visweswara Rao…[et al.]. A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-16.
https://search.emarefa.net/detail/BIM-1205853
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pasupuleti, Visweswara Rao& Arigela, Chandra Sekhar& Gan, Siew Hua& Salam, Sirajudeen Kuttulebbai Nainamohamed& Krishnan, Kumara Thevan& Rahman, Nurhanan Abdul…[et al.]. A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-16.
https://search.emarefa.net/detail/BIM-1205853
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1205853
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر