ROS from Physical Plasmas: Redox Chemistry for Biomedical Therapy
المؤلفون المشاركون
Wende, Kristian
Weltmann, Klaus-Dieter
Bekeschus, Sander
Schmidt, Anke
Bogaerts, Annemie
Privat-Maldonado, Angela
Lin, Abraham
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-29، 29ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-08
دولة النشر
مصر
عدد الصفحات
29
التخصصات الرئيسية
الملخص EN
Physical plasmas generate unique mixes of reactive oxygen and nitrogen species (RONS or ROS).
Only a bit more than a decade ago, these plasmas, operating at body temperature, started to be considered for medical therapy with considerably little mechanistic redox chemistry or biomedical research existing on that topic at that time.
Today, a vast body of evidence is available on physical plasma-derived ROS, from their spatiotemporal resolution in the plasma gas phase to sophisticated chemical and biochemical analysis of these species once dissolved in liquids.
Data from in silico analysis dissected potential reaction pathways of plasma-derived reactive species with biological membranes, and in vitro and in vivo experiments in cell and animal disease models identified molecular mechanisms and potential therapeutic benefits of physical plasmas.
In 2013, the first medical plasma systems entered the European market as class IIa devices and have proven to be a valuable resource in dermatology, especially for supporting the healing of chronic wounds.
The first results in cancer patients treated with plasma are promising, too.
Due to the many potentials of this blooming new field ahead, there is a need to highlight the main concepts distilled from plasma research in chemistry and biology that serve as a mechanistic link between plasma physics (how and which plasma-derived ROS are produced) and therapy (what is the medical benefit).
This inevitably puts cellular membranes in focus, as these are the natural interphase between ROS produced by plasmas and translation of their chemical reactivity into distinct biological responses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Privat-Maldonado, Angela& Schmidt, Anke& Lin, Abraham& Weltmann, Klaus-Dieter& Wende, Kristian& Bogaerts, Annemie…[et al.]. 2019. ROS from Physical Plasmas: Redox Chemistry for Biomedical Therapy. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-29.
https://search.emarefa.net/detail/BIM-1206070
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Privat-Maldonado, Angela…[et al.]. ROS from Physical Plasmas: Redox Chemistry for Biomedical Therapy. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-29.
https://search.emarefa.net/detail/BIM-1206070
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Privat-Maldonado, Angela& Schmidt, Anke& Lin, Abraham& Weltmann, Klaus-Dieter& Wende, Kristian& Bogaerts, Annemie…[et al.]. ROS from Physical Plasmas: Redox Chemistry for Biomedical Therapy. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-29.
https://search.emarefa.net/detail/BIM-1206070
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206070
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر