Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment
المؤلفون المشاركون
Lv, Longqin
Mao, Shanping
Dong, Huimin
Fang, Congcong
Liu, Baohui
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-24
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Parkinson’s disease (PD) is the second most common progressive neurodegenerative disorder mainly in middle-elderly population, which represents diverse nonmotor symptoms (NMS) besides such well-documented motor symptoms as bradykinesia, resting tremor, rigidity, and postural instability.
With the advancement of aging trend worldwide, the global prevalence of PD is mounting up year after year.
Nowadays, accumulating lines of studies have given a comprehensive and thorough coverage of motor symptoms in PD.
Yet much less attention as compared has been paid to the nonmotor symptoms of PD, such as cognition deficits.
Of note, a patient with PD who suffers from cognitive impairment may harbour a statistically significantly higher risk of progressing toward dementia, which negatively affects their life expectancy and daily functioning and overall lowers the global quality of life.
Furthermore, it is a widely held view that cognitive dysfunction does not just occur in the late stage of PD.
On the basis of numerous studies, mild cognitive impairment (MCI) is a harbinger of dementia in PD, which is observed as an intermediate state with considerable variability; some patients remain stable and some even revert to normal cognition.
Considered that the timing, profile, and rate of cognitive impairment vary greatly among PD individuals, it is extremely urgent for researchers and clinicians alike to identify and predict future cognitive decline in this population.
Simultaneously, early screening and canonical management of PD with cognitive deficits are very imperative to postpone the disease progression and improve the prognosis of patients.
In our review, we focus on a description of cognitive decline in PD, expound emphatically the pathological mechanisms underlying cognition deficits in PD, then give a comprehensive overview of specific therapeutic strategies, and finally dissect what fresh insights may bring new exciting prospect for the subfield.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fang, Congcong& Lv, Longqin& Mao, Shanping& Dong, Huimin& Liu, Baohui. 2020. Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment. Parkinson’s Disease،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1206400
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fang, Congcong…[et al.]. Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment. Parkinson’s Disease No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1206400
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fang, Congcong& Lv, Longqin& Mao, Shanping& Dong, Huimin& Liu, Baohui. Cognition Deficits in Parkinson’s Disease: Mechanisms and Treatment. Parkinson’s Disease. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1206400
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206400
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر