Wearable Sensors Measure Ankle Joint Changes of Patients with Parkinson’s Disease before and after Acute Levodopa Challenge
المؤلفون المشاركون
Zhang, Wenbin
Xu, Pingyi
Wu, Zhuang
Jiang, Xu
Zhong, Min
Shen, Bo
Zhu, Jun
Pan, Yang
Dong, Jingde
Zhang, Li
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Previous studies found levodopa could improve the activity of the ankle joints of patients with Parkinson’s disease (PD).
But ankle joint movement is composed of four motion ranges.
The specific changes of four motion ranges in PD remain unknown.
Objective.
The purpose of this study was to decompose the complex ankle joint movement, measure ankle joint changes before and after the acute levodopa challenge test (ALCT), and investigate the effects of these parameters on gait performance.
Methods.
29 PD patients and 30 healthy control subjects (HC) completed the Instrumented Stand and Walk (ISAW) test and gait parameters were collected by the JiBuEn gait analysis system.
The percentage of improvement of gait data and the UPDRS III in the on-drug condition (ON) were determined with respect to the off-drug condition (OFF).
Results.
We observed a reduction in the heel strike angle (HS), 3-plantarflexion (3-PF) angle, and 4-dorsiflexion (4-DF) angle of ankle joints.
We did not find significant difference in the toe-off angle (TO), 1-plantarflexion (1-PF) angle, and 2-dorsiflexion (2-DF) angle among three groups.
Stride length improvement rate was significantly correlated with HS (rs = 0.616, P<0.001) and 3-PF (rs = 0.639, P<0.001) improvement rates.
The improvement in the sum of rigidity items (UPDRS motor subsection item 22) was also correlated with HS (rs = 0.389, P=0.037) and 3-PF (rs = 0.373, P=0.046) improvement rates.
Conclusions.
Exogenous levodopa supplementation can significantly reduce the rigidity of patients with PD, improve their 3-PF and 4-DF of ankle joint kinematic parameters, and ultimately enhance their gait.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Zhuang& Jiang, Xu& Zhong, Min& Shen, Bo& Zhu, Jun& Pan, Yang…[et al.]. 2020. Wearable Sensors Measure Ankle Joint Changes of Patients with Parkinson’s Disease before and after Acute Levodopa Challenge. Parkinson’s Disease،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1206439
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Zhuang…[et al.]. Wearable Sensors Measure Ankle Joint Changes of Patients with Parkinson’s Disease before and after Acute Levodopa Challenge. Parkinson’s Disease No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1206439
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Zhuang& Jiang, Xu& Zhong, Min& Shen, Bo& Zhu, Jun& Pan, Yang…[et al.]. Wearable Sensors Measure Ankle Joint Changes of Patients with Parkinson’s Disease before and after Acute Levodopa Challenge. Parkinson’s Disease. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1206439
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206439
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر