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Neutrophil Oxidized-Modified Proteins and Neutrophil Extracellular Traps in Patients with Community-Acquired Pneumonia
المؤلفون المشاركون
Molotov-Luchanskiy, Vilen
Nukhuly, Altynbek
Muravlyova, Larissa
Bakirova, Ryszhan
Kossybayeva, Aruna
Klyuyev, Dmitry
Demidchik, Ludmila
Beinikova, Irina
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-16
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background and Objectives.
Community-acquired pneumonia (CAP) has a high mortality rate among adult patients throughout the world.
The highest mortality is registered in the older age group with a steady increase in the number of cases of morbidity among persons of working age.
Neutrophils are one of the most urgent areas of research, since their condition largely determines the development and outcome of acute pneumonia.
We study the indices of oxidative stress and oxidized-modified proteins of neutrophils in CAP patients, depending on the degree of severity, and also compare the detection frequency of neutrophil extracellular traps in the progression of pneumonia.
Materials and Methods.
51 patients with CAP were divided into 2 groups depending on the severity of the pathological process.
The first group (I) consisted of 32 patients with moderate severity of pneumonia.
The second group (II) consisted of 19 patients with severe pneumonia.
The third group (III), the comparison group, consisted of 14 CAP patients with chronic obstructive pulmonary disease (COPD).
The control group consisted of 19 volunteers.
Results.
Statistically significant increase in the level of carbonyl derivatives (CD) in patients of all study groups relative to the control group was revealed.
In the group of patients with moderate severity and severe pneumonia, also in CAP patients with COPD, the level of CD exceeded the control group.
There was no statistically significant difference in the level of advanced oxidation protein products (AOPP) and myeloperoxidase (MPO) in blood neutrophils between the studied groups.
Conclusion.
Results indicate an oxidative imbalance in neutrophils and contribute to the worsening of the course of the disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Molotov-Luchanskiy, Vilen& Nukhuly, Altynbek& Muravlyova, Larissa& Bakirova, Ryszhan& Kossybayeva, Aruna& Klyuyev, Dmitry…[et al.]. 2020. Neutrophil Oxidized-Modified Proteins and Neutrophil Extracellular Traps in Patients with Community-Acquired Pneumonia. Pulmonary Medicine،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1206554
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Molotov-Luchanskiy, Vilen…[et al.]. Neutrophil Oxidized-Modified Proteins and Neutrophil Extracellular Traps in Patients with Community-Acquired Pneumonia. Pulmonary Medicine No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1206554
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Molotov-Luchanskiy, Vilen& Nukhuly, Altynbek& Muravlyova, Larissa& Bakirova, Ryszhan& Kossybayeva, Aruna& Klyuyev, Dmitry…[et al.]. Neutrophil Oxidized-Modified Proteins and Neutrophil Extracellular Traps in Patients with Community-Acquired Pneumonia. Pulmonary Medicine. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1206554
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1206554
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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